Mapping MHC class II genes and disease susceptibility. Methods Mol Biol 1993; 15: 95.Bain S, Todd J (1993) Mapping MHC Class II genes and Dis- ease-Susceptibility. In: White B (ed.) PCR Protocols: Cur- rent Methods and Applications. Humana Press Inc, Totowa, pp 95±112...
Bontrop RE. 1997. MHC class II genes of nonhuman primates. In: Molecular biologyBontrop, R. E: MHC class II genes of nonhuman primates. In: Molecular biology and evolution of blood group and MHC antigens in primates. Eds Blancher, A. Klein, J & W. W. Socha, Springer-Verlag, ...
近日，来自瑞士University of Lausanne的Alexandre Harari和David Gfeller研究组在Immunity上发表题为Machine learning predictions of MHC-II specificities reveal alternative binding mode of class II epitopes的文章，就上述问题进行了深入探讨。人类的MHC-II也被称之为HLA-II，包含有三个可以直接给CD4+T细胞递呈抗原的...
The highly regulated pattern of expression of the gene encoding CIITA dictates where, when and to what level MHC class II genes are expressed. Transcription of the gene encoding CIITA is controlled by a large regulatory region that contains three independent promoters (pI, pIII and pIV). These ...
2.1CIITA: The Master Transcriptional Regulator of MHC Class II Genes MHCclass II molecules are heterodimericglycoproteinscomposed of a α and aβ chain, which are constitutively displayed at the surface of professional antigen-presenting cells (APCs) such as dendritic cells (DCs), macrophages, and ...
MHC class IIAIDS modelTo find new HIV-1 inhibitors with excellent activities against not only wild-type HIV-1 strans but also HIV-1 mutants.doi:10.1016/j.meegid.2017.10.015Lian, Xiao-DongZhang, Xi-HeDai, Zheng-XiZheng, Yong-Tang
典型MHC基因的多态性较普通的多态性基因复杂得多(如与ABO血型抗原基因比较)多态性变异较为集中于HLA分子与抗原肽结合部位的结构域许多多态性变异基因并未发现其对应的表达分子,PolymorphisminMHCClassIgenes,D.uk/HIG/index.htmlOctober2003,998alleles(657inJuly2000),PolymorphisminMHCClassIIgenes,D.uk/HIG/index.ht...
近日,来自瑞士University of Lausanne的Alexandre Harari和David Gfeller研究组在Immunity上发表题为Machine learning predictions of MHC-II specificities reveal alternative binding mode of class II epitopes的文章,就上述问题进行了深入探讨。 人类的MHC-II也被称...
MHC class II genes in HCV viral clearance of hepatitis C infected Hispanic patients 来自 Semantic Scholar 喜欢 0 阅读量: 36 作者:J Azocar,OP Clavijo,EJ Yunis 摘要: The frequency of class II human leukocyte antigen (HLA) alleles in 112 infected patients of Hispanic ancestry with serology ...
27、marelated gene 1 to activate transcription of major histocompatibility complex class II genesJ. Mol Cell Biol, 2002, 22(14): 5019-5026.8 Kanazawa S, Okamoto T, Peterlin BM. Tat competes with CIITA for the binding to PTEFb and blocks the expression of MHC class II genes in HIV infecti...