HLA-DR3 can be expressed as a transgene on CD4+ T cells in complete MHC Class II knock-out (AEo) mice, but not in I-Ab knock-out (Abo) mice, suggesting that a gene, which could modify the expression of HLA-DR3, might exist between I-A and I-E. Expression sequence tag (EST)...
In humans, the MHC class II protein complex is encoded by the human leukocyte antigen gene complex (HLA). HLAs corresponding to MHC class II are HLA-DP, HLA-DM, HLA-DOA, HLA-DOB, HLA-DQ, and HLA-DR (3). In the literature, this clone is ...
C57BL/6 mouse splenocytes were unstained (left) or stained with 0.4 µg of MHC Class II (I-A/I-E) Monoclonal Antibody, NovaFluor Yellow 660 (right). All cells were co-stained with CD3e (145-2C18) Monoclonal Antibody, eFluor 450 (Product # 48-0031-89). Total ...
Description: The M5/114.15.2 monoclonal antibody reacts with the mouse major histocompatibility complex class II, both I-A and I-E subregion-encoded glycoproteins (I-A b, I-A d, I-A q, I-E d, I-E k, not I-A f, I-A k, or I-A s). It detects a polymorphic determinant pres...
Gene-knockout mice carrying deletions of the corresponding mouse gene (C2ta) also show most features of the human disease. The highly regulated pattern of expression of the gene encoding CIITA dictates where, when and to what level MHC class II genes are expressed. Transcription of the gene ...
MHC class II I E kappa Mouse mAb (PE),来自阿拉丁,Aladdin的所有抗体均在WB、IP、IHC、ChIP或ICC/IF中进行了验证,并在小鼠、大鼠、人、酿酒酵母、非洲爪蟾、拟南芥中进行了测试…
提供的MHC Class II (I-A/I-E)单克隆抗体, 克隆号M5/114。15。2产品克隆号为M5/114。15。2,对应的亚型为IgG2b, kappa。该基因又称,全名为,对应Gene号为,其蛋白编号为。 应用类型 WB,IHC,Func,Flow Cyt 免疫原 Mouse MHC Class II (I-A/I-E)。
mouse models, accompanied by an increase in macrophage major histocompatibility complex (MHC) class II expression and T cell effector function. Mechanistically, PAD4 citrullinatesSTAT1at arginine 121, thereby promoting the interaction between STAT1 andprotein inhibitor of activated STAT1(PIAS1), and ...
In mouse bone marrow GM-CSF DC system, three distinct developmental stages differentiated by their MHC class II compartmentalization have been identified (Pierreet al., 1997). MHC class II in immature DCs accumulates inlysosomesinstead of trafficking to the cell surface. As maturation progresses, MH...
The M5/114.15.2 monoclonal antibody or (M5/114) is specific for the mouse major histocompatibility complex class II, specific for the I-A and I-E subregion-encoded glycoproteins (alloantigens I-Ab, I-Ad, I-Aq, I-Ed, and I-Ek, but not the I-Af, I-Ak, nor I-As antigens). Th...