MHC Class II基因有许多别称,如HLA-D region(人类白细胞抗原-D区域)、Ia gene(Ia基因)等。这些别称来源于基因所在的位置和功能。在我国,MHC Class II基因的研究已取得丰硕成果,为免疫学、遗传学等领域的发展做出了巨大贡献。 【五、总结】 MHC Class II基因作为免疫系统中的关键分子,其研究不仅在基础科学领域具...
Extensive MHC class II B gene duplication in a passerine, the common yellowthroat Geothlypis trichas . J Hered. 2010.Bollmer JL, Dunn PO, Whittingham LA, Wimpee C. Extensive MHC Class II B Gene Duplication in a Passerine, the Common Yellowthroat ( Geothlypis trichas ) J Heredity. 2010; ...
This complex gene-expression profile is controlled almost exclusively by a single master regulatory factor, which is known as the class II transactivator. As we discuss here, differential activation of the three independent promoters that drive expression of the gene encoding the class II ...
Class Monoclonal Type Antibody Full Name histocompatibility 2, class II antigen A, alpha Synonyms Aalpha, H 2Aa, H2Aa, H2-Aa, Ia 1, Ia1, IAalpha, MHC Class II GenBank Accession Number BC031711 Gene Symbol MHC Class II Gene ID (NCBI) 14960 RRID AB_2883788 Conjugate FITC Plus Fluoresc...
Description: The M5/114.15.2 monoclonal antibody reacts with the mouse major histocompatibility complex class II, both I-A and I-E subregion-encoded glycoproteins (I-A b, I-A d, I-A q, I-E d, I-E k, not I-A f, I-A k, or I-A s). It detects a polym...
21.2.2MHC Class II TheMHCclass II molecule (MHCII) is composed of twopolypeptide chains, α and β, each of which traverses the cell membrane and associates to form aheterodimercontaining two conserved immunoglobulin-like domains proximal to the cell membrane (α2β2) and two polymorphic domai...
提供的MHC Class II (I-A/I-E)单克隆抗体, 克隆号M5/114。15。2产品克隆号为M5/114。15。2,对应的亚型为IgG2b, kappa。该基因又称,全名为,对应Gene号为,其蛋白编号为。 应用类型 WB,IHC,Func,Flow Cyt 免疫原 Mouse MHC Class II (I-A/I-E)。
蛋白别名:A alpha; cell surface glycoprotein; H-2 class II histocompatibility antigen, A beta chain; H-2 class II histocompatibility antigen, A-B alpha chain; H-2 class II histocompatibility antigen, A-F alpha chain; H-2 class II histocompatibility antigen, A-K alpha chain; H-2 class II...
Structural basis for mouse LAG3 interactions with the MHC class II molecule I-Ab Lymphocyte activation gene-3 (LAG3) is an immune checkpoint protein recently approved as a target for anti-melanoma therapy. Here, the authors solve the structure of mouse LAG3 bound to MHC-II to show that ...