HLA-DR3 can be expressed as a transgene on CD4+ T cells in complete MHC Class II knock-out (AEo) mice, but not in I-Ab knock-out (Abo) mice, suggesting that a gene, which could modify the expression of HLA-DR3, might exist between I-A and I-E. Expression sequence tag (EST)...
Description: The M5/114.15.2 monoclonal antibody reacts with the mouse major histocompatibility complex class II, both I-A and I-E subregion-encoded glycoproteins (I-A b, I-A d, I-A q, I-E d, I-E k, not I-A f, I-A k, or I-A s). It detects a polym...
Description: The M5/114.15.2 monoclonal antibody reacts with the mouse major histocompatibility complex class II, both I-A and I-E subregion-encoded glycoproteins (I-A b, I-A d, I-A q, I-E d, I-E k, not I-A f, I-A k, or I-A s). It detects a polymorphic determinant pres...
上海玉博生物科技有限公司 主要致力于“anti-mouse Ea52-68 peptide bound to the I-A(b)/MHC Class II Gene Products Purif eBioscience-14-5741-82”的生产销售。多年的“anti-mouse Ea52-68 peptide bound to the I-A(b)/MHC Class II Gene Products Purif eBioscience-
Inflammatory stimuli induce accumulation of MHC class II complexes on dendritic cells. Nature 388, 782–787 (1997). CAS PubMed Google Scholar Pierre, P. et al. Developmental regulation of MHC class II transport in mouse dendritic cells. Nature 388, 787–792 (1997). Article CAS PubMed ...
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Here, we evaluated MHC variation (allelic richness and divergence) and patterns of selection acting on the two highly polymorphic MHC class II loci (DRB and DQB) in the endangered primate Madame Berthe's mouse lemur (Microcebus berthae). Using 454 pyrosequencing, we exam- ined MHC variation ...
In the case of non-carnivore mammals, heterozygosity of the DRB gene in a population of the striped mouse (Rhabd- omys pumilio), has been shown to influence infection status [21]. A low level of diversity at the DAB locus (an MHC class II gene in marsupials) in the western barred ...
single loci and differences in MHC class II gene duplication numbers across haplotypes [167]. At the moment it is not clear whether or not this selection pattern of intermediate, rather than maximal allele numbers is confined to species with a relatively flexible genomic architecture such as stickl...
II expression was forced at the DP thymocyte stage21,22. Both the mouse lines were generated by expressing the human class II MHC transactivator (CIITA) under the control of CD4 or proximal Lck promotor regions. Consequently, in both transgenic mice, MHC II was expressed on DP thymocytes. ...