Twenty-eight alleles of MHC class I genes were identified using CE-SSCP (capillary electrophoresis-single strand conformation polymorphism) method in this study. In malarial endemic region (i.e. low and intermediate altitudes), MHC allele Almo* 05 was identified as a determinant factor in malarial...
Boyson et al., The MHC class I genes of the rhesus monkey, J. Immunol. 156:4656-4665, 1996.Boyson JE, Shufflebotham C, Cadavid LF et al. The MHC class I genes of the rhesus monkey. Different evolutionary histories of MHC class I and II genes in primates. J Immunol 1996; 156: ...
We cloned, sequenced and transfected the MHC class I genes from three other species of bone-chimeric primates (the saddle-backed tamarin, S. fuscicollis; the common marmoset, Callithrix jacehus; and the golden-headed lion tamarin, Leontopithecus rosalia) and a single species of a non-bone ...
典型MHC基因的多态性较普通的多态性基因复杂得多(如与ABO血型抗原基因比较)多态性变异较为集中于HLA分子与抗原肽结合部位的结构域许多多态性变异基因并未发现其对应的表达分子,PolymorphisminMHCClassIgenes,D.uk/HIG/index.htmlOctober2003,998alleles(657inJuly2000),PolymorphisminMHCClassIIgenes,D.uk/HIG/index.ht...
MHC Class I MHC class Imolecules are composed of a polymorphic chain and a non-polymorphic invariantβ chain(B2M) linked by a noncovalent interaction.MHC class Igenes are categorized intoclassical (MHC class Ia)(HLA-A, -B, -C, seeGlossary) ornonclassical (MHC class Ib)(HLA-E, -F, -G...
The MHC class I genes, which mediate allogeneic ... H Dirscherl,JA Yoder - 《Immunogenetics》 被引量: 23发表: 2014年 Alternative haplotypes of antigen processing genes in zebrafish diverged early in vertebrate evolution Antigen processing and presentation genes found within the MHC are among the ...
Dynamic Diversity of Antigen Processing and Histocompatibility Genes within the Zebrafish Core MHC Class I Locus 1058 The zebrafish is an important animal model for stem cell biology, cancer, and immunology research. Histocompatibility represents a key intersection of... S Mcconnell,R Kettleborough,I ...
In mice, Cd1 genes are located on chromosome 3, and the gene encoding the neonatal intestinal Fc receptor maps to chromosome 7. Thus, all of the currently known mouse class I genes encoded outside the MHC are dispersed to separate chromosomes. 16 refs., 2 figs....
MHC class I regulatory element (CREPROBLEM: The regulation of classical HLA class I genes in choriocarcinoma have been reported.METHODS: We determined whether four choriocarcinoma cell lines expressed classical HLA class I or HLA-G by a reverse transcription-polymerase chain reaction (RT-PCR) and ...
On the biological front, despite the fact that both MICA and HLA class I genes and molecules have a similar and unique tri-dimensional structure, major differences exist in their respective functions, for example HLA class I require both the β2-microglobulin and an endogenously derived peptide ...