Major histocompatibility complex (MHC) class II molecules are polymorphic antigens encoded by four gene loci in the mouse: Aα, Aβ, Eα, and Eβ. Non-covalent association of appropriate α and β chains results in the stable cell surface expression of the two isotypic forms: I-A and I...
Description: The M5/114.15.2 monoclonal antibody reacts with the mouse major histocompatibility complex class II, both I-A and I-E subregion-encoded glycoproteins (I-A b, I-A d, I-A q, I-E d, I-E k, not I-A f, I-A k, or I-A s). It detects a poly...
Description: The M5/114.15.2 monoclonal antibody reacts with the mouse major histocompatibility complex class II, both I-A and I-E subregion-encoded glycoproteins (I-A b, I-A d, I-A q, I-E d, I-E k, not I-A f, I-A k, or I-A s). It detects a polymorphic ...
Gene-knockout mice carrying deletions of the corresponding mouse gene (C2ta) also show most features of the human disease. The highly regulated pattern of expression of the gene encoding CIITA dictates where, when and to what level MHC class II genes are expressed. Transcription of the gene ...
Molecular analyses of genes in the rabbit MHC (RLA) by pulsed field gel electrophoresis have shown that the relative order of class II genes (DP, DO, DQ, DR) is identical to that in humans and similar to that in the mouse. However, a maj... L Chouchane,TJ Kindt - 《Journal of Imm...
mouse models, accompanied by an increase in macrophage major histocompatibility complex (MHC) class II expression and T cell effector function. Mechanistically, PAD4 citrullinatesSTAT1at arginine 121, thereby promoting the interaction between STAT1 andprotein inhibitor of activated STAT1(PIAS1), and ...
Description: This AF6-120.1 monoclonal antibody reacts with the mouse MHC Class II I-Ab alloantigen of H-2b bearing mouse strains, including C57Bl/6 and 129. This cell surface molecule is involved in antigen presentation to T cells expressing CD3/TCR and CD4. ...
提供的MHC Class II (I-A/I-E)单克隆抗体, 克隆号M5/114。15。2产品克隆号为M5/114。15。2,对应的亚型为IgG2b, kappa。该基因又称,全名为,对应Gene号为,其蛋白编号为。 应用类型 WB,IHC,Func,Flow Cyt 免疫原 Mouse MHC Class II (I-A/I-E)。
Invitrogen Anti-MHC Class II (I-A) Monoclonal (NIMR-4), eBioscience™, Catalog # 12-5322-81. Tested in Flow Cytometry (Flow) applications. This antibody reacts with Mouse samples. Supplied as 50 µg purified antibody (0.1 mg/mL).
In mouse bone marrow GM-CSF DC system, three distinct developmental stages differentiated by their MHC class II compartmentalization have been identified (Pierreet al., 1997). MHC class II in immature DCs accumulates inlysosomesinstead of trafficking to the cell surface. As maturation progresses, MH...