(2002) Genetic control of MHC class II expression. Cell, 109(Suppl), S21-S33.Ting JP, Trowsdale J: Genetic control of MHC class II expression. Cell 109(Suppl):S21, 2002Ting JP, Trowsdale J. Genetic control of MH
Genetic control of MHC class II expression. Cell (2002) 109(Suppl.):S21-33. doi: 10.1016/S0092-8674(02)00696-7Ting JP-Y, Trowsdale J (2002) Genetic Control of MHC Class II Expression. Cell 109, S21-S33. - 30 -Ting, J.P. and Trowsdale, J. (2002) Genetic control of MHC ...
Genetic control of MHC class II expression. Cell 109 Suppl, S21–33 (2002). 26. Steimle, V., Otten, L. A., Zufferey, M. & Mach, B. Complementation cloning of an MHC class II transactivator mutated in hereditary MHC class II deficiency (or bare lymphocyte syndrome). 1993. J Immunol...
Fig. 1: Inference of HLA-I tumor status with LILAC. a, Representation of the six immune escape pathways considered in the present study alongside their associated genes (adapted from ‘MHC class I and II pathways’, by BioRender.com). The genes considered for each immune escape pathway are ...
However, the basal or LPS-inducible expression of individual genes varied independently by as much as 100-fold between subjects. Extreme independent variation in the expression of pairs of HLA-associated transcripts (HLA-B/C, HLA-A/F and HLA-DRB1/DRB5) in macrophages was associated with HLA ...
55,56 Peptide binding to the antigen peptide occurs through two mechanisms: (1) a sequence-independent mode involving the formation of hydrogen bonds between the backbone of the peptide and conserved residues of the MHC class II binding site and (2) a sequence-dependent interaction mode in ...
1A). Resulting peptides may or may not be exocytosed or displayed in the context of nascent MHC class II molecules, upon displacement of the invariant chain (Ii) in the CII vesicles. Since degradation of proteins in endolysosomes greatly precludes preservation of conformational B-cell epitopes,...
The polymorphism of class II HLA genes modulates the genetic risk for several endocrine autoimmune diseases. The constitutive class II expression on antigen-presenting cells is under the control of the MHC class II transactivator, encoded by the MHC2TA gene, which is mapped to chromosome 16p13. ...
Normalized and centered expression levels of MHC class I, class II, interferon, and complement genes were compared, per sample, between all cells with upregulation of MHC-related genes (score > 1) and all cells without such upregulation (score < 0). The average differential expression...
BMC Genomics (2025) 26:115 https://doi.org/10.1186/s12864-025-11281-x BMC Genomics RESEARCH Open Access Influence of MHC on genetic diversity and testicular expression of linked olfactory receptor genes Mingue Kang1, Byeongyong Ahn1, Jae Yeol Shin1, Hye-Sun Cho1, Jongan Lee2 ...