Thus, CD4 cells are known as helper cells because they influence the production of B cells, which make antibodies, clonal expansion of memory T-cells, and result in many other growth factors which can in turn destroy bacteria, allergens, etc.Weber...
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T cells apparently are not tolerant and can respond to such rare Id-peptides. Note that an otherwise rare Id-peptide may upon clonal expansion, like e.g. in multiple myeloma, become frequent and induce T-cell tolerance. [Normal View ] 展开 ...
Plating efficiency is used to assess the ability of serum to facilitate cell adherence to solid surfaces for growth. One common assay for this uses A549 human lung carcinoma cells, plated at low density in media supplemented with 5-10% FBS, and monitored for attachment and clonal growth after ...
Clonal expansion of mycobacterial heat-shock protein-reactive T lymphocytes in the synovial fluid and blood of rheumatoid arthritis patients To examine the reactivity pattern and T cell receptor (TCR) characteristics of mycobacterial heat-shock protein 65 (hsp65)-reactive T cells generated from ... ...
Identification and expansion of the tumorigenic lung cancer stem cell population. Cell Death Differ. 15, 504–514 (2008). Article CAS PubMed Google Scholar Hermann, P. C. et al. Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer....
When an animal is immunized with a protein, different B cells recognize different epitopes, giving rise to multiple B cell populations. If the blood is collected and the antibodies purified from the serum, the resultant product will contain antibodies from all of those B cell clones, hence the...
17 Although the evolution pattern varied from lesion to lesion, it was suggested that the early central hyperintensity phase might be related to the demyelination of oligodendroglia accompanied by cellular infiltration and an expansion of the extracellular spaces that have been observed on electron ...
Fusion to Create Hybridoma Cells As spleen cells have limited survival times in culture, they require fusion with myelomas, cancerous B-Cells, to create an immortalized hybrid that can undergo many passagesin vitro. This is achieved through polyethylene glycol (PEG) or electric pulses both of wh...
Due to its enriched cell composition with a high density of immune cells. These include myeloid immune cells such as resident macrophages called Kupffer cells (KC), neutrophils, or lymphoid cells such as NK, NKT, T and B lymphocytes. As such, the liver is considered an immunological organ. ...