Sfikakis, P.P.; Karali, V.; Lilakos, K.; Georgiou, G.; Panayioditis, P. Clonal expansion of B-cells in human systemic lupus erythematosus: evidence from studies before and after therapeutic B-cell depletion. Clin. Immunol. 2009, 132, 19-31....
HIV viremia can be controlled by chronic antiretroviral therapy. As a potentially single-shot alternative, B cells engineered by CRISPR/Cas9 to express anti-HIV broadly neutralizing antibodies (bNAbs) are capable of secreting high antibody titers. Here, we show that, upon immunization of mice, adop...
Somatic mutation and clonal expansion of B cells in an antigen-driven immune response. EMBO J. 4, 345–350 (1985). Article CAS PubMed PubMed Central Google Scholar Briney, B.S., Willis, J.R., Finn, J.A., McKinney, B.A. & Crowe, J.E. Jr. Tissue-specific expressed antibody ...
Antigen-driven clonal expansion of B cells infiltrating salivary glands and lymph nodes in patients with Sjoegren's syndrome. 来自 yadda.icm.edu.pl 喜欢 0 阅读量: 15 作者:S Jahn,S Gellrich,A Borkowski,S Golembowski,S Rutz,E Gromnicaihle,W Sterry ...
germinal center B cell clonal expansion cyclin D3 FOXO1 c-Myc cyclin D2 B cell non-Hodgkin lymphoma B-NHL Introduction The human immune system is the warden of local and global cellular fitness, protecting the health of bodily functions. B cells act at the forefront of providing lifelong immu...
Facebook Twitter Google Share on Facebook clonal (redirected fromclonal expansion) Thesaurus Medical Financial Encyclopedia Related to clonal expansion:Clonal selection (klōn) n. 1.A group of cells or organisms that are descended from and genetically identical to a single progenitor, such as a bact...
Clonal expansion of Epstein–Barr virus (EBV)-infected γδ T cells in patients with chronic active EBV disease and hydroa vacciniforme-like eruptions 来自 Semantic Scholar 喜欢 0 阅读量: 50 作者:T Wada,A Toga,Y Sakakibara,T Toma,M Hasegawa,K Takehara,T Shigemura,K Agematsu,A Yachie ...
Furthermore, while ICOS-B7RP-1 interactions have no effect on the migration of T cells into B cell follicles, it is essential for their ability to support B cell responses. 展开 关键词: Inducible Costimulatory MoleculeBRelated Interactions Important Expansion Functions ...
2024年12月16日,Genentech公司Ira Mellman团队在期刊《Nature Cancer》上发表了题为“TIGIT and PD-L1 co-blockade promotes clonal expansion of multipotent, non-exhausted antitumor T cells by facilitating co-stimulation”的研究论文。研究结果表明,PD-1和TIGIT抑制有助于形成引流淋巴结中对肿瘤有反应的CD8 T细...
We also showed that marginal-zone B cells may cycle and that clones of B cells are frequently detected in the nodal as well as the splenic marginal zone. These clones are not related to those present in adjacent germinal centers. These data favor the hypothesis that clonal expansion occurs ...