ResponseProduction and Clonal Expansion in a Th1 g Induction in Postdifferentiation IFN-B k T Cell-Intrinsic Requirement for NF-Mark NF- (cid:1) B/Rel transcription factors are linked to innate immune responses and APC activation. Whether and how the induction of NF- (cid:1) B signaling ....
Consider the bottom portion of the curves in Figure 1: patients with MRD who do not relapse.Various scenarios could account for this finding, including residual clones of lesser pathogenicity and/or immune restraint of clonal expansion (see above). Alternatively, could this be due to persisten...
This process is sometimes referred to as a clonal expansion. Why this malignant clone should escape from normal body controls is unclear, though there are a number of interesting, and perhaps competing, hypotheses and we will discuss these shortly.Tariq I. Mughal...
aFailure to anticipate and plan for implementation challenges early in the project 疏忽对实施挑战期望和计划及早在项目 [translate] a我在跟他说我们学校的情况 I in said our school to him the situation [translate] aSeveral artificial immune algorithms have been developed imitating the clonal selection ...
Instead, they downregulate NK1.1 expression and undergo marked but transient clonal expansion to ten times their steady-state levels. NK1.1 expression remains reduced on antigen-experienced NKT cells for at least 12 days. Article CAS PubMed PubMed Central Google Scholar Park, S. H., Kyin, ...
is lower than estimated earlier by Fischer et al. [71], possibly reflecting low donor numbers in both studies and/or different duration of ART. The advantage of this method is that CA RNA is sequenced, which allows determining the intactness/defectiveness, as well as clonal expansion, of the...
It will be argued that this multistage, multimechanism model of carcinogenesis, involving the “initiation” of a single cell by a mutagen event, followed by chronic exposure to threshold levels of epigenetic agents or conditions that stimulate the clonal expansion of the �...
The hybridoma cloning test measures the ability of a serum lot to support clonal growth of a hybridoma or myeloma cell line. Typically, a hybridoma cell line is plated at low density in a 96-well plate containing media supplemented with 5-10% FBS. High grade FBS should see high and consis...
Evolution of resistance and progression to disease during clonal expansion of cancer. Theor. Popul. Biol. 77, 42–48 (2010). Article PubMed Google Scholar Harnevo, L. E. & Agur, Z. The dynamics of gene amplification described as a multitype compartmental model and as a branching process....
The clonal expansion and anatomic location of microbe-specific CD4+ Th cells was studied by tracking the fate of adoptively transferred DO11.10 TCR transgenic T cells specific for OVA peptide 323-339/I-Ad in BALB/c mice infected s.c. with Escherichia coli expressing a MalE-OVA fusion protein...