Thus, CD4 cells are known as helper cells because they influence the production of B cells, which make antibodies, clonal expansion of memory T-cells, and result in many other growth factors which can in turn destroy bacteria, allergens, etc.Weber...
T cells apparently are not tolerant and can respond to such rare Id-peptides. Note that an otherwise rare Id-peptide may upon clonal expansion, like e.g. in multiple myeloma, become frequent and induce T-cell tolerance. [Normal View ] 展开 ...
Recent years have seen so-called natural killer T (NKT) cells emerge as important regulators of the immune response. The existence of NKT-cell subsets, and other types of T cell that resemble NKT cells, is an ongoing source of confusion in the literature. This perspective article seeks to ...
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Identification and expansion of the tumorigenic lung cancer stem cell population. Cell Death Differ. 15, 504–514 (2008). Article CAS PubMed Google Scholar Hermann, P. C. et al. Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer....
role of NK cells and T cells in multiple sclerosis Chu Xie, Signal Transduction and Targeted Therapy, 2024 Automated Classification of Intramedullary Spinal Cord Tumors and Inflammatory Demyelinating Lesions Using Deep Learning Zhizheng Zhuo, Radiology: Artificial Intelligence, 2022 mTOR Inhibitor Therapy ...
B cells and T cells are the major cell types involved in adaptive immunity. Of these, it is the B cells that are responsible for antibody production. Antibody production by B cells B cells are produced in the bone marrow before migrating to the spleen and entering the circulatory system. ...
The clonal expansion and anatomic location of microbe-specific CD4+ Th cells was studied by tracking the fate of adoptively transferred DO11.10 TCR transgenic T cells specific for OVA peptide 323-339/I-Ad in BALB/c mice infected s.c. with Escherichia coli expressing a MalE-OVA fusion protein...
Martin J. Blaser is at the Department of Medicine and the Department of Microbiology, New York University Langone Medical Center, New York, New York 10017, USA., Martin J. Blaser Stanley Falkow is at the Department of Microbiology and Immunology and the Department of Medicine, Stanford Universit...
Increasing evidence suggests that LPC expansion occurs within a particular microenvironment requiring cellular interactions with non-parenchymal and immune cells. Chronic non-resolving inflammation and tissue damage contribute to the activation of LPC compartment and regulate several mechanisms. It leads to th...