Immunology LettersYong-Joon Chwae,In-Hong Choi,Dong-Soo Kim,Eui-Cheol Shin,Dae-Ho Kwon,Se-Jong Kim,Joo-Deuk Kim.Clonal expansion of T-cells in measles[J]. Immunology Letters .1998(3)Chwae YJ; Choi IH; Kim DS;.Clonal expansion of T- cells in measles.Immunol Lett.1998.147-152...
Clonal T cell expansion is the process of T cell activation and proliferation which occurs naturally in vivo when the human body is actively fighting an infection or an immune system attack. In vitro, clonal T cell expansion happens when a naïve T cell recognizes and binds to a...
值得注意的是,其他control peptide刺激下,Shannon diversity 和 baseline 相比并没有变化,提示 α-myosin 是 clonal T cell expansion的强刺激剂。 Fig4b:为了评估α-myosin-expanded TCR clones是否参与心脏和骨骼肌毒性,作者将心脏和受累肌肉的TCR β chain repertoires与在α-myosin exPBMCs 中高表达(与unexpanded ...
0.02, **p = 0.007 from left to right. Source data are provided as a Source Data file.DUniform manifold approximation and projection (UMAP) of the distribution of T cell clones in bone marrow T cells from healthy adults, MGUS/SMM and MM patients.EBar chart showing clonal distribution in...
F. CD8 T cell clonal expansion and development of effector function require prolonged exposure to antigen, costimulation, and signal 3 cytokine. J. Immunol. 171, 5165–5171 (2003). Article CAS PubMed Google Scholar Agarwal, P. et al. Gene regulation and chromatin remodeling by IL-12 and ...
Clonal expansion of myelin basic protein-reactive T cells in patients with multiple sclerosis: Restricted T cell receptor V gene rearrangements and CDR3 se... Myelin basic protein (MBP)-reactive T cells are thought to play an important role in the pathogenesis of multiple sclerosis (MS). In ...
相关研究结果近期发表在Nature Cancer期刊上,论文标题为“Clonal expansion of T memory stem cells determines early anti-leukemic responses and long-term CAR T cell persistence in patients”。 对Pt4和Pt6中的CD3+细胞进行免疫表型分析,图片来自Nature Cancer, 2021, doi:10.1038/s43018-021-00207-7。
22 Considering the different functions and recognition patterns of CD4+ and CD8+ T cells and the clonal expansion of both subsets in RA, we decided to study the frequencies and the molecular properties of CD4−CD57+ and of CD4+CD57+ cells in RA patients. We report that, among the 25 ...
JARED K, ALISHA C, NATHAN D, Clonal expansion of vaccine-elicited T cells is independent of aerobic glycolysis [J]. SCIENCE IMMUNOLOGY. 2018, 3(27): eaas9822. 来源 https://medicalxpress.com/news/2018-09-discovery-cell-behavior-major-implications.html ...
相关研究结果近期发表在Nature Cancer期刊上,论文标题为“Clonal expansion of T memory stem cells determines early anti-leukemic responses and long-term CAR T cell persistence in patients”。 对Pt4和Pt6中的CD3+细胞进行免疫表型分析,图片来自Nature Cancer, 2021, doi:10.1038/s43018-021-00207-7。 这些...