Linnemann T, Gellrich S, Lukowsky A, Mielke A, Audring H, Sterry W, et al. Polyclonal expansion of T cells with the TCR Vbeta type of the tumour cell in lesions of cutaneous T-cell lymphoma: evidence for possible super- antigen involvement. Br J Dermatol 2004;150:1013e7....
(+) T cell lymphocytes expansion also has therapeutical consequences since patients with an organ infiltration or a neutropenia may respond remarkably to immunomodulatory therapies. The search of a CD8(+)/CD57(+) T cell expansion thus represents a useful and still poorly known diagnostic tool ...
The search of a CD8(+)/CD57(+) T cell expansion thus represents a useful and still poorly known diagnostic tool which clinical interest deserves further evaluation. 展开 关键词: CHRONIC LYMPHOCYTIC-LEUKEMIA BONE-MARROW-TRANSPLANTATION COMMON VARIABLE IMMUNODEFICIENCY IN-VITRO INHIBITION VERSUS-HOST-...
If a retrovirus vector is to be used for this transduction, activation of the T-cells is required for integration of the transgene to occur. The activation protocol should ensure expansion of a broad repertoire of donor T-cells. Notably, T-cells specific for herpes virus family antigens are ...
Vβ21.3+ T cells from MIS-C patients expressed high levels of HLA-DR, CD38 and CX3CR1 but had weak responses to SARS-CoV-2 peptides in vitro. Consistently, the T cell expansion was not associated with specific classical HLA al...
T cell expansion; Cytokines; Costimulatory molecules ☆ This work was supported by Grant NS-52177 from the National Institute of Health, and Grants RG3499 and RG3701 from the National Multiple Sclerosis Society (T.G.F.). Corresponding author. Address: Dept. of Biology, University of Texas...
On pegilodecakin, newly expanded T cell clones, undetectable at baseline, become 1%–10% of the total T cell repertoire in the blood. Elevation of interleukin-18, expansion of LAG-3+ PD-1+ T cells and novel T cell clones each correlated with objective tumor responses. Combined pegilodeca...
A T cell activity that enhances polyclonal IgE production and its inhibition by interferon-gamma. Polyclonal activation of the murine immune system by an antibody to IgD. IV. In vivo activation of B lymphocytes from immune defecti... Ex vivo expansion of polyclonal and antigen-specific cytotoxic...
CLEC2A (C-type lectin domain family 2 member A), also known as PILAR (proliferation-induced lymphocyte-associated receptor) is involved in modulating T-cell expansion. It is a 32 kDa single-pass type II membrane protein that contains one C-type lectin domain in its extracellular region and ...
CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production. CD4+CD25+ Immunoregulatory T Cells Suppress Polyclonal T Cell Activation In Vitro by Inhibiting Interleukin 2 ProductionPeripheral tolerance may be maintained ... A,M,Thornton,......