Clonally expanded B cells in multiple sclerosis bind EBV EBNA1 and GlialCAMMultiple sclerosis (MS) is a heterogenous autoimmune disease in which autoreactive lymphocytes attack the myelin sheath of the central nervous system (CNS). B lymphocytes in the cerebrospinal fluid (CSF) of MS patients ...
B-cell differentiation in the CNS of patients with multiple sclerosis Clonally expanded populations of Ig variable gene-mutated B cells are found in the central nervous system (CNS) of subjects with multiple sclerosis (MS), s... A Corcione,F Aloisi,B Serafini,... - 《Autoimmunity Reviews》 ...
CD4+CD28− costimulation-independent T cells in multiple sclerosis. J. Clin. Invest. 108, 1185–1194 (2001). Article CAS PubMed PubMed Central Google Scholar Schmidt, D., Goronzy, J. J. & Weyand, C. M. CD4+ CD7- CD28- T cells are expanded in rheumatoid arthritis and are ...
Clonally expanded CD3+, CD4-, CD8- cells bearing the alpha/beta or the gamma/delta T-cell receptor in patients with the lymphoproliferative disease of gran... Among 60 retrospectively assessed patients with the lymphoproliferative disease of granular lymphocytes (LDGL), lymphocytes from only 2 pati...
Distribution of double-negative (CD4- CD8-, DN) T subsets in blood and synovial fluid from patients with rheumatoid arthritis Double-negative (CD4- CD8-) T (DNT) cells have been postulated to be potentially autoreactive. However, the role of DNT cells in rheumatoid arthritis (RA) ... MF...
Clonally expanded CD4(+) T cells can produce infectious HIV-1 in vivo 2016. Clonally expanded CD4+ T cells can produce infectious HIV-1 in vivo. Proc. Natl.Acad. Sci. USA. 113:1883-1888. http://dx.doi... - 《Proceedings of the National Academy of Sciences》 被引量: 59...
Predominance of activated, clonally expanded T helper type 17 cells within the CD4+ T cell population in psoriatic lesions. Predominance of activated, clonally expanded T helper type 17 cells within the CD4+ T cell population in psoriatic lesions. Clin Exp Immunol. 2013; 173 ... BJ Lewis,S ...
However, sequence analysis revealed multiple repetitive and clonally related transcripts at distant colonic sites from all VH families. This suggests that, in addition to a polyclonal B-cell pool, subsets of B cells are clonally expanded and widely distributed along the colon. Occasionally, there ...
P01horn H; Herrmann M; Harms H;.Apoptotic cells and clonally expanded cytotoxic T cells in bone marrow trephines of patients with myelodysplastic syndrome.Histopathology.2012.200-211Plilhom H,Herrmann M,Harms H,et al.Apoptotic cells and clonally expanded cytotoxic T cells in bone marrow trephines...
Notably, by utilizing multiple single cell TCR sequencing strategies on a third cohort, we discovered clonally expanded CD8+ TEMRA cells in patient cerebrospinal fluid (CSF). Finally, we used machine learning, cloning, and peptide screens to demonstrate specificity of clonally expanded AD CSF TCRs ...