Our results indicate that heat stress suppressed the immune response level via the NLRC3-like protein, the fine-tuning of protein turnover activity, and ATP metabolism. This might disrupt the balance of coral-zooxanthellae symbiosis and result in the bleaching of the coral A. aculeus. (C) ...
Suppression of NF-kB signal pathway by NLRC3-like protein in stony coral Acropora aculeus under heat stress. Fish. Shellfish Immunol. 67, 322e330. ... Li,Can,Wang,... - 《Fish & Shellfish Immunology》 被引量: 3发表: 2017年 Suppression of NF-kappa B signal pathway by NLRC3-like pro...
An example is protein NLRC3 (CARD15-like protein, caterpiller protein 16.2, nucleotide-binding oligomerization domain protein, 1065aa) that may modulate T-cell activation. See cryopyrin. CATH database An hierarchical domain classification of protein structures in the Protein Data Bank (PDB). Protein...
We found that NLRC3 indeed decreases NALP3-induced IL-1β maturation and secretion, pro-caspase-1 cleavage, and speck formation by apoptosis-associated speck-like protein containing a CARD (ASC) protein in response to NALP3 activators. We also show that endogenous NLRC3 interacts with both ASC...
A large number of experimental studies at home and abroad have demonstrated that NLRC3 protein plays a significant regulatory role in the proliferation and apoptosis of cancer cells.The NLRC3 protein plays an important role in the proliferation and apoptosis of cancer cells. High expression of NLRC...
NLRC5 expression can be induced by toll-like receptor (TLR) ligands like LPS and poly(I:C), interferons, or viral infec- tion, but the most prominent effect is observed with IFN-γ [1, 7-10]. IFN-γ is a potent stimulator of MHC class I expression, which requires NLRC5 expression ...
In the present study in adult spotted snakehead we have investigated the sex-dependent tissue distribution of NLRs known to be associated with inflammation in teleost namely NOD1, NOD2, NLRC3, NLRC5, and NLRX1. Further, the sexual dimorphism in the expression of NLR transcript as well as the...
Using human monocytic-like U937 cells, Yang et al. (2009) find that receptor-associated protein (RAP) inhibits APC-induced phosphorylation of adaptor protein disabled-1 (Dab1), Akt and glycogen synthase kinase 3β, whereas anti-EPCR or anti-PAR-1 blocking antibodies did not. Knocking down ...
ASC foci(ASC焦点),英文全称为apoptosis-associated speck-like protein containing a caspase recruitment domain foci,即含有caspase募集结构域焦点的凋亡相关斑点样蛋白,这是一个多聚体蛋白,由炎症小体蛋白的同源寡聚引发的螺旋原纤维形成。 Familial Mediterranean fever(家族性地中海热):一种常染色体隐性遗传性自身炎...
The association rate constant in TransComp is cal- ccrTkauaornnaslaenvdtsasoe,Cldmutoheamdsesikppfkof.rouneFnsdo=viirocaentlkuexo0adaennmsbedcypxaΔlpTel(c,rG−afuoenller∆asitCtseGhodteemhlcebe/opykemwBloeTpiuctl)thre,rxwomthCshotoheadsrteeieeYclck/iaaoCn0nlrctheieuserclAtaalhcot(...