Our results indicate that heat stress suppressed the immune response level via the NLRC3-like protein, the fine-tuning of protein turnover activity, and ATP metabolism. This might disrupt the balance of coral-zooxanthellae symbiosis and result in the bleaching of the coral A. aculeus. (C) ...
1f). Together, our results indicated that wild-type Gp54Bas11, like the previously identified MCP from phage SECΦ27, activates CapRelSJ46. CapRel antitoxin directly senses Gp54 CapRelSJ46 consists of a conserved N-terminal toxin domain that can pyrophosphorylate tRNAs and a C-terminal ...
Moreover, rMIC1 but not rMIC1-T126A/T220A was found to be able to upregulate NOD-like receptor pyrin domain-containing protein 3 (NLRP3) and activate GSDMD and caspase-1 in BMDMs but not in TLR4−/− and NLRP3−/− BMDMs. Conclusions TgMIC1 is implicated in both parasite ...
An example is protein NLRC3 (CARD15-like protein, caterpiller protein 16.2, nucleotide-binding oligomerization domain protein, 1065aa) that may modulate T-cell activation. See cryopyrin. CATH database An hierarchical domain classification of protein structures in the Protein Data Bank (PDB). Protein...
An example is protein NLRC3 (CARD15-like protein, caterpiller protein 16.2, nucleotide-binding oligomerization domain protein, 1065aa) that may modulate T-cell activation. See cryopyrin. CATH database An hierarchical domain classification of protein structures in the Protein Data Bank (PDB). Protein...
in complex biological mixtures like cell lysates or tissue extracts, the presence of many proteins and contaminants makes data interpretation difficult and requires thorough sample preparation and purification. LiP-MS may not be appropriate for insoluble proteins, particularly membrane proteins. LiP-MS off...
Leukocyte mono-immunoglobulin-like receptor 8 (LMIR8)/CLM-6 is an FcRγ-coupled receptor selectively expressed in mouse tissue plasmacytoid dendritic cells.Mono(2-ethylhexyl) phthalate accelerates early folliculogenesis and inhibits steroidogenesis in cultured mouse whole ovaries and antral follicles. ...
ICE protease activating factor; Ice protease-activating factor; Ipaf; LRR; NLR family CARD domain containing 4; NLR family CARD domain-containing protein 4; NLRC 4; NLRC4; NLRC4_HUMAN; NOD like receptor C4; Nucleotide binding oligomerization domain leucine rich repeat and CARD domain containing...
(Apoptosis-associated speck-like protein containing a caspase recruitment domain foci). These multimeric protein aggregates result from helical fibril formation that is initiated by the homo-oligomerization of inflammasome proteins. Familial Mediterranean fever ...
Using human monocytic-like U937 cells, Yang et al. (2009) find that receptor-associated protein (RAP) inhibits APC-induced phosphorylation of adaptor protein disabled-1 (Dab1), Akt and glycogen synthase kinase 3β, whereas anti-EPCR or anti-PAR-1 blocking antibodies did not. Knocking down ...