Suppression of NF-kB signal pathway by NLRC3-like protein in stony coral Acropora aculeus under heat stress. Fish. Shellfish Immunol. 67, 322e330. https://doi.org/10.1016/j.fsi.2017.06.027.Zhou Z, et al. Suppression of NF-kappaB signal pathway by NLRC3-like protein in stony coral ...
Penaeus vannamei NLRP3-like Regulate Antimicrobial peptides 1. Introduction Inflammation underlined a serious of physiological and pathological processes in mammals, which trigger immune system defenses against internal or external threats [1,2]. Pathogen induced inflammatory response relies on pattern-recogn...
2M). Compared with wild-type microglia, TXNIP-deficient microglia showed an enhanced trend of transformation to the M1-like phenotype, whereas silencing TXNIP did not have a significant influence on M2-like microglial polarization (Fig. 4C–F, Supplementary Fig. 2J,K, Fig. 5C–F, Supplementary...
Excessive inflammatory responses induced upon SARS-CoV-2 infection are associated with severe symptoms of COVID-19. Inflammasomes activated in response to SARS-CoV-2 infection are also associated with COVID-19 severity. Here, we show a distinct mechanism
In the present study in adult spotted snakehead we have investigated the sex-dependent tissue distribution of NLRs known to be associated with inflammation in teleost namely NOD1, NOD2, NLRC3, NLRC5, and NLRX1. Further, the sexual dimorphism in the expression of NLR transcript as well as the...
in complex biological mixtures like cell lysates or tissue extracts, the presence of many proteins and contaminants makes data interpretation difficult and requires thorough sample preparation and purification. LiP-MS may not be appropriate for insoluble proteins, particularly membrane proteins. LiP-MS off...
Leukocyte mono-immunoglobulin-like receptor 8 (LMIR8)/CLM-6 is an FcRγ-coupled receptor selectively expressed in mouse tissue plasmacytoid dendritic cells.Mono(2-ethylhexyl) phthalate accelerates early folliculogenesis and inhibits steroidogenesis in cultured mouse whole ovaries and antral follicles. ...
The activation of the Nlrc4 inflammasome requires the presence of an intact type III or IV secretion system that mediates the translocation of small amounts of flagellin or PrgJ-like rod proteins into the host cytosol to induce Nlrc4 activation. Using the Salmonella system, it was shown that...
Like in the unweighted network analysis permutation was used to determine significance threshold. Through this weighted network analysis approach we discovered 11 additional mediator candidates, examples being the rs61598054 -> FOXO3 -> AKT1 -> NGF and the rs693918 -> XDH -> T...
Fig. 3. General structure of CCN family members. Insulin-like growth factor-binding protein domain (IGFBP), type C repeat of von Willebrand factor domain (VWC), type 1 repeat of thrombospondin domain (TSP1), C-terminal domain (CT) and signal peptide (SP). The functions carried out by CC...