language = {eng}, month = {12}, pages = {1--4}, publisher = {Springer New York}, series = {Encyclopedia of Signaling Molecules}, title = {Src-Like Adapter Protein 2 (SLAP2)}, url = {http://dx.doi.org/10.1007/978-1-4614-6438-9_101669-1}, volume = {2}, year = {2016},...
SRC-like adaptor protein 2 (SLAP2) binds to wild-type KIT in a ligand-dependent manner and is furthermore found constitutively associated with the oncogenic mutant KIT-D816V. Peptide fishing analysis mapped pY568 and pY570 as potential SLAP2 association sites in KIT, which overlaps with the ...
产品名称:Recombinant Human Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN 中文名称: WRN重组蛋白 别名:(DNA helicase, RecQ-like type 3)(RecQ3)(Exonuclease WRN)(RecQ protein-like 2) 纯度: Greater than 85% as determined by SDS-PAGE. 基因名: WRN Uniprot No.: Q14191 别...
Figure 2.Phosphoregulation of GABAAR endocytosis. The endocytosis of GABAARs is regulated by the interaction of the AP2 complex with β and γ2 subunits. Phosphorylation of β3 (S408/S409) and γ2 (Y365/Y367) by PKA/PKC and Src/Fyn, respectively, prevents binding to AP2 and thus stabi...
Protein domainthat mediates binding to phosphorylatedtyrosineresidues; src homology 2. Protein domain that mediates binding to proline-rich (PxxP) regions; src homology 3. View chapterExplore book Proteomics Kung-HaoLiang, inBioinformatics for Biomedical Science and Clinical Applications, 2013 ...
MAL, a novel integral membrane protein of human T lymphocytes, associates with glycosylphosphatidylinositol-anchored proteins and Src-like tyrosine kinases. Eur... J Millán,MA Alonso - 《European Journal of Immunology》 被引量: 47发表: 2015年 Membrane insertion and antibody recognition of a glycosy...
This protein class shares a common NTF2-like domain which, in case of G- members, localizes to the periplasm of the respective host47. In contrast, TraH resisted proteolytic degradation in protease protection assays using E. faecalis protoplasts, suggest- ing a reversed topology where the C-...
A more advanced example that restricts modeling to certain domains within a sequence is like the follows A|19-200;500-700:2/B/C 1788 A2BC where the residue ranges, 19 to 200 and 500 to 700, are taken out from A's full length input features for modeling A2BC, composed of two copies...
Interestingly, mutation of the palmitoylated cysteine residues of the SRC kinases LYN and FYN and the adapter molecule LAT prevents the association of these proteins with lipid rafts (Shenoy-Scariaet al., 1994; W.Zhanget al., 1998b), although it is difficult to attribute such effects to the...
1–6). Interestingly, the WSME-L model can explain the differences in the folding pathways of two proteins with similar structures, src and α-spectrin SH3 domains (Supplementary Figs. 2 and 3). Therefore, the WSME-L model quantitatively improves the prediction accuracy of the folding ...