language = {eng}, month = {12}, pages = {1--4}, publisher = {Springer New York}, series = {Encyclopedia of Signaling Molecules}, title = {Src-Like Adapter Protein 2 (SLAP2)}, url = {http://dx.doi.org/10.1007/978-1-4614-6438-9_101669-1}, volume = {2}, year = {2016},...
SRC-like adaptor protein 2 (SLAP2) binds to wild-type KIT in a ligand-dependent manner and is furthermore found constitutively associated with the oncogenic mutant KIT-D816V. Peptide fishing analysis mapped pY568 and pY570 as potential SLAP2 association sites in KIT, which overlaps with the ...
Protein phosphorylation is recognized as the primary mechanism for the transduction of extracellular stimuli into intracellular events (Cohen, 1982; Nestler et al.,1984). Ineukaryotes, for example, all of the biochemical actions of cAMP have been attribu
(presented as surface representation). In the case of the tyrosine kinase c-SRC (PDB:2SRC), this is due to a threonine residue occupying the so-called gate-keeper position in the 5th β-stand of the N-lobe, ensuring fidelity of phospho-turnover cycles inherent to cellular homeostasis.C)...
产品名称: Recombinant Human Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN 中文名称: WRN重组蛋白 别名: (DNA helicase, RecQ-like type 3)(RecQ3)(Exonuclease WRN)(RecQ protein-like 2) 纯度: G
84 As compared to agonists which facilitate G protein and β-arrestin signaling at the same time, a β-arrestin-biased agonist for δ-opioid receptor can effectively control anxiety-like behaviour by activating ERK1/2 in the limbic structures of the brain.85 Hence, identifying therapeutic ...
Protein domainthat mediates binding to phosphorylatedtyrosineresidues; src homology 2. Protein domain that mediates binding to proline-rich (PxxP) regions; src homology 3. View chapterExplore book Proteomics Kung-HaoLiang, inBioinformatics for Biomedical Science and Clinical Applications, 2013 ...
formation of spiky filopodia actin structures [13]. Ena/VASP can also interact with WRC through ABI1 to enhance lamellipodia formation and migration [14]. VASP and associated proteins enabled homolog (ENAH) and Ena/VASP-like (EVL) were identified as ABI1 proximal interactors (Fig. 2AB) [6]...
but only need the.fmidatabase file. Whilekaijuxtakes nucleotide sequences as input and translates them into the six reading frames like standardkaiju,kaijuptakes protein sequences as input, which are directly searched in the database. All other parameters remain the same as in standardkaiju. In...
2.Specify a div in your html 3.Create an instance of FeatureViewer in JavaScript with the sequence (or a length), the div in which it will be display and the rendering options of your choice. varft=newFeatureViewer.createFeature('MALWMRLLPLLALLALWGPGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLE'...