英文名称:Crk Like Protein (CRKL) Polyclonal Antibody,中文名称:Crk样蛋白(CRKL)多克隆抗体,产品货号:CAU22165,[其他名称:V-Crk肉瘤病毒CT10癌基因同源物(禽类)免疫原:CRKL(Met1~Glu303)验证反应性:智人(人类)验证应用:WB、ICC、IHC-P、IH
Crk-like protein (CRKL) is a protein kinase containing SH2 and SH3 (src homology) domains which activates the RAS and JUN kinase signaling pathways and transforms fibroblasts in a RAS-dependent manner. CRKL is a substitute of the BCR-ABL tyrosine kinase, it also has a role in fibroblast ...
Crk-like (CrkL) is a key signaling protein that mediates the leukemogenic activity of Bcr-Abl. Structural investigations show that the intramolecular assembly of CrkL is entirely distinct from that of CrkII, shedding light on how CrkL specifically mediates Bcr-Abl signaling.doi:10.1038/nchembio....
[below right]Fig 1. "Immunohistochemical detection and analysis of CrkL protein in gliomas" Two panels overlap after a 90-deg flip. How can they be IHC stains for different proteins?
1A). Similarly, the protein level of GFP in the cell population as measured by Western analysis displayed a similar trend (Fig. 1B). Time-lapse analysis of live fibroblasts transfected with synGFP showed strong GFP signals at 5 h post transduction, with the fluorescence reaching a maximum ...
V-crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like Human Recombinant Shipping:Ice Packs Synonyms Crk-like protein, CRKL. Introduction Crk-like protein (CRKL) is a protein kinase containing SH2 and SH3 (src homology) domains which activates the RAS and JUN kinase signaling pathways and tr...
Its deduced amino acid sequence shows homology to the SH2 domains of protein tyrosine kinases such as FER, and is strikingly similar to the cellular part of the v-crk oncogene product. We identified one SH2 and two SH3 domains within the 303 amino acid open reading frame of this crk-...
Abstract The natural variation between Arabidopsis ( Arabidopsis thaliana ) ecotypes Columbia (Col) and Landsberg erecta (Ler) strongly affects abscisic acid (ABA) signalling and drought tolerance. Here, we report that the cysteine‐rich receptor‐like protein kinase CRK4 is involved in regulating AB...
SummaryProtein kinases play important roles in relaying information from perception of a signal to the effector genes in all organisms. Cysteine-rich receptor-like kinases (CRKs) constitute a sub-family of plant receptor-like kinases (RLKs) with more than 40 members that contain the novel C-X8...
Crk-like adapter protein is required for TGF- beta-induced AKT and ERK-signaling pathway in epithelial ovarian carci- nomas. Tumour Biol 2015;36:915e9. http://dx.doi.org/10.1007/s13277-014- 2724-0. PubMed PMID: 25307974.Shaomei Cheng, Jingyan Guo, Qing Yang, Lin Han. (2015) Crk-...