Nuclear RNA-seq of single neurons reveals molecular signatures of activation. Nat. Commun. 7, 11022 (2016).Benjamin Lacar, Sara B. Linker, Baptiste N. Jaeger, Suguna Krishnaswami, Jerika Barron, Martijn Kelder, 642 Sarah Parylak, Apu藴a Paquola, Pratap Venepally, Mark Novotny, Carolyn O'...
How to cite this article:Lacar, B.et al. Nuclear RNA-seq of single neurons reveals molecular signatures of activation.Nat. Commun.7:11022 doi: 10.1038/ncomms11022 (2016). Accession codes Accessions Gene Expression Omnibus GSE77067 In the original version of this Article, the middle names or ...
Quadrant analyses reveal sub-populations of CM.a–cQuadrant analysis for Proliferation vs. Negative regulators of proliferation genes identifies increased co-expression in individual TAC nuclei (Q2; 44.4%;p = 3.237e−07Fisher’s exact test), only detectable by single nuclear RNA-seq (a),...
Remarkably, only 0.49–3.37% of the nucleomorph genomes of these organisms did not have any mRNA counterpart in our RNA-Seq data sets, and nucleomorph genes show equal or higher levels of transcription than their counterparts in the nuclear genomes. We hypothesize that elevated levels of nucleo...
Chromatin-enriched RNAs mark active and repressive cis-regulation: an analysis of nuclear RNA-seq Long noncoding RNAs ( lncRNAs ) localize in the cell nucleus and influence gene expression through a variety of molecular mechanisms. RNA sequencing of two biochemical fractions of nuclei reveals a uniq...
In some samples, tDRs (tRFs and tRHs) are the most abundant class of smRNAs found in smRNAseq datasets, more so than even miRNAs. Nevertheless, unlike miRNAs, the biological functions of tDRs largely remain undefined. 2.3 Small Nuclear RNA In the nucleus, there is a diverse array of ...
优异的细胞质和核RNA分离和纯化;方便快捷的旋转柱形式;高质量和高产量的RNA;在没有苯酚的情况下分离完整多样性的RNA(包括microRNA);纯化的RNA可用于任何应用,包括RT-PCR,qRT-PCR,RNA-Seq,微阵列等;细胞质RNA不含DNA,可直接用于RT-PCR / qRT-PCR。
In Physcomitrium patens, PpRH1/PpRH2 are GUCT-domain-containing DEAD-BOX RNA helicases localize to the nucleus. They are implicated in cell and tissue development in all stages of the moss life cycle. Abstract The DEAD-box-containing RNA helicase family encompasses a large and functionally...
RNA-sequencing showed that 8.5% of TNF-± transcriptional responses were TonEBP-dependent and identified genes regulated by both TNF-± and TonEBP. These genes were over-enriched in pathways and diseases related to Inflammatory Response and Inhibition of Matrix Metalloproteases. Based on RNA-seq ...
In fact, components of ripoptosome and inflammasome cascades were upregulated and they were significantly correlated in GBMs of the TCGA-RNASeq dataset. Moreover, an increased apoptotic rate was observed when the GBM-derived U87MG cells were co-treated with LPS and Temozolomide (TMZ) in ...