高通量测序技术省去了烦琐的Small RNA克隆文库构建过程,可以一次性生成上百万条Small RNA序列,能够快速鉴定特定条件下表达的已知Small RNA并发现新的Small RNA,同时还可以研究不同条件下Small RNA的表达差异,并可以联合转录组测序表达谱数据进行关联分析。 A workflow for Small RNA SequencingJai PM et al., RNA Ma...
高通量测序技术省去了烦琐的Small RNA克隆文库构建过程,可以一次性生成上百万条Small RNA序列,能够快速鉴定特定条件下表达的已知Small RNA并发现新的Small RNA,同时还可以研究不同条件下Small RNA的表达差异,并可以联合转录组测序表达谱数据进行关联分析。 A workflow for Small RNA Sequencing Jai PM et al., RNA...
Reddy R & Busch H (1988) In: Birnstiel ML (Ed) Structure and Function of the Major and Minor Small Nuclear Ribonucleoprotein Particles (pp 1–37). Springer-Verlag, New YorkReddy R and Busch H ( 1988 ) Small nuclear RNAs: RNA sequences, structure, and modifications . In Birnstiel,M....
Small Nuclear RNA (snRNA) refers to a class of highly abundant RNA molecules, localized in the nucleus, that play important roles in intron splicing and other RNA processing. They form ribonucleoprotein particles (snRNPs) and function as part of a large complex called the spliceosome, which media...
We used small RNA deep sequencing to profile Ang II-regulated miRNAs in rat vascular smooth muscle cells (VSMC) and evaluated their role in VSMC dysfunction. Sequencing results revealed several Ang II-responsive miRNAs, and bioinformatics analysis showed that their predicted targets can modulate ...
GRP20 has a putative nuclear localization signal (NLS, residues 12 to 25; Fig. 1b); however, there were no annotated domains in the C-terminal region. We used the catRAPID and RNAbindPlus programs to investigate whether GRP20 could potentially bind to RNA (Extended Data Fig. 1a). The ...
【解析】snRNA(small nuclear RNA):小RNA,即 small nuclear RNA之缩写,也称为核内低分子RNA。广泛存在于真核生物的细胞核中,为一组代谢稳定的低分子RNA之总称。因分子种类不同,有的可出现于细胞质中。已知在哺乳类动物中有多种,如U1A,U1B,U1C,U2U3A,U3B,U4,U6,4.5SI.4.5SⅡ,4.5SⅢ,5SⅢ等。由于这些...
Transfer RNA (tRNA)-derived small RNAs (tsRNAs), a novel category of small noncoding RNAs, are enzymatically cleaved from tRNAs. Previous reports have shed some light on the roles of tsRNAs in the development of human diseases. However, our knowledge abo
百度试题 题目snRNA(Small nuclear RNA) 相关知识点: 试题来源: 解析 是细胞核内的小RNA,它是真核生物转录后加工过程中RNA剪接体(spilceosomE.的主要成分,参与mRNA前体的加工过程。 反馈 收藏
Partial characterization of these RNAs, based on cell fractionation, polyacrylamide gel electrophoretic and chemical sequencing techniques, as well as comparison with literature data, revealed that, in addition to tRNA, 5S RNA and 5.8S RNA, plant nuclei contain two families of low-molecular-mass ...