Genes specifying long non-coding RNAs (lncRNAs) occupy a large fraction of the genomes of complex organisms. The term 'lncRNAs' encompasses RNA polymeraseI (Pol I), PolII andPolIII transcribed RNAs, and RNAs fro
Non-coding RNAs (ncRNAs) are ribonucleic acid (RNA) molecules that are not translated into protein products. Different classes of non-coding RNAs participate in different cellular processes; for example, gene expression regulation (miRNAs, piRNAs, lncRNAs), RNA maturation (snRNAs, snoRNAs) and prot...
1.和siRNA一样装载成RISC(RNA induced silencing complex , RISC;沉默复合物)后互补配对的mRNA降解; 2.miRNA可抑制mRNA的翻译,降低靶基因的蛋白质水平但不影响期mRNA的水平。 三、lncRNA(long non-coding RNA) IncRNA的长度一般大于200bp。根据基因组位点或相关的DNA特征,可以进一步进行分类(图4): 图4 长链非...
Non-codingRNAsare those RNAs that do not undergo the translation process ofprotein synthesis. Non-codingRNA(ncRNA) molecules are transcribed from more than 70% of the genome. More than 40 different types ofnon-coding RNAsare known and they are mostlyribosomal RNAs(rRNAs), transfer RNAs (tRNAs...
Non-coding RNA Research aims to publish high quality research and review articles on the mechanistic role of non-coding RNAs in all human diseases. This interdisciplinary journal will welcome research dealing with all aspects of non-coding RNAs-their biogenesis, regulation and role in disease … Vi...
ncRNA为蛋白质编码的RNA分子,而是在细胞内执行其他功能。ncRNA基因有许多类型,其中一些包括: 转移RNA(tRNA):tRNA负责在蛋白质合成过程中将氨基酸带到核糖体上。有20种不同的tRNA基因,每种基因都编码一种特定的氨基酸。 核糖体RNA(rRNA):rRNA是核糖体的主要组成部分,是负责合成蛋白质的细胞机器。有几种不同类型的rR...
Definition and nomenclature of lncRNAs lncRNAs have been arbitrarily defined as non-coding transcripts of more than 200 nucleotides (200 nt), which is a convenient size cut-off in biochemical and biophysical RNA purification protocols that deplete most infrastructural RNAs, such as 5S rRNAs, tRNAs,...
Non-codingRNA:Versatilityinformandfunction NoncodingRNAgenesaresurprisinglynumerous.NoncodingRNAhaveaverydifferentfunctions.TimeforRNomics Cell,89:669–672,May30,1997 PNAS,97(26):14035-14037,Dec19,2000 UnderstandingRNomicsfromanexpendingsnoRNAworld CouzinJ.Breakthroughoftheyear.SmallRNAsmakebigsplash.Science...
Noncoding DNA Noncoding DNA Noncoding RNA noncoercive noncognitive Noncognitivism noncoherent Noncoherent Decision-Feedback Equalization Noncoherent Frequency Shift Keying Noncoherent M-ary Amplitude Shift Keying noncoherent pulse radar noncoherent scattering Noncoherent Trellis-Coded Modulation Noncohesion non...
non-coding rna名词解释non-coding rna名词解释 非编码RNA(non-coding RNA,ncRNA)指的是在转录成RNA时不被翻译成蛋白质的RNA分子。与编码蛋白质的mRNA相比,ncRNA的功能非常多样,包括调控基因表达、RNA的剪接和稳定性、染色体转录后修饰等。非编码RNA是生物学研究领域中的一个热门话题,对于揭示细胞及多细胞生命现象的...