Non-coding (nc) RNA plays a vital role in biological processes and has been associated with diseases such as cancer. Classification of ncRNAs is necessary for understanding the underlying mechanisms of the dise
ClassificationResearch methodMechanismTherelationshipwithmajordisease 1.Introduction NoncodingRNA(ncRNA)isakindoftranscriptswithouttheabilityofcodingproteins,whichexistwidelyinhighlyeukaryotic.TheamountofthencRNAtranscriptsisupto98％ofthewholegenome’stranscripts.Thedifferenceinmolecularstructureandexpressive...
1、NoncodingRNA非编码RNA 1Repertor:Xiaoning Yuan Oct.9.2012Irnne.MP,Cheng G,Wieland.S,et al,2007NoncodingRNA非编码RNANoncoding RNAvIntroductionvClassification vResearch method vMechanism vThe relationship with major diseaseNoncodingRNA非编码RNA1.Introduction Noncoding RNA(ncRNA) is a kind of transc...
2The Long and Short of Noncoding RNAs Defined by size,ncRNAmolecules are classified as either short (<200nt) or long (>200nt). Longnoncoding RNAs(lncRNAs) are a heterogeneous group (see below for classification) that can reach multiple kilobases in length and are predominantly located in the...
Dayanara Ruiz-Ojeda, Carlos A Guzmán-Martín, Rafael Bojalil, Ximena F Balderas, Iris S Paredes-González, Javier González-Ramírez, Enrique Torres-Rasgado, Adrián Hernández-DíazCouder, Rashidi Springall & Fausto Sánchez-Muñoz. (2024)Long noncoding RNA MALAT1 in dermatologic disorders: a ...
Figure 1. LncRNA classification according to their orientation and position in the genome. (G, Latgé.;et al, 2018) LncRNA Functions LncRNAs, despite lacking protein-coding potential, regulate gene expression, chromatin remodeling, and cell cycle. Heterogeneously expressed, they act at multiple lev...
LncRNAs can be categorized in terms of length, function, location, and targeting mechanism and currently there is no unified standard for their classification. According to their position in the genome relative to protein-coding genes, they can be classified as sense, antisense, bidirectional, ...
NoncodingRNA非编码RNA_生物学_自然科学_专业资料。Repertor:Xiaoning Yuan Oct.9.2012 Irnne.MP,Cheng G,Wieland.S,et al,2007 Noncoding RNA ? Introducti Repertor:Xiaoning Yuan Oct.9.2012 Irnne.MP,Cheng G,Wieland.S,et al,2007 Noncoding RNA ? Introduction ? Classification ? Research method ?
biological context is available, we recommend naming the lncRNA according to the GENCODE system46. The wide range of functions of ‘non-coding’ RNAs precludes straightforward classification as specific RNA classes, with some acting locally and some at a distance, or both62. In the absence of ...
Non-coding (nc) RNA plays a vital role in biological processes and has been associated with diseases such as cancer. Classification of ncRNAs is necessary for understanding the underlying mechanisms of the diseases and to design effective treatments. Recently, deep learning has been employed for ...