The discovery of peptides encoded by what were thought to be non-coding – or 'junk' – regions of precursors to microRNA sequences reveals a new layer of gene regulation. These sequences may not be junk, after
The advent of high-throughput sequencing uncovered that our genome is pervasively transcribed into RNAs that are seemingly not translated into proteins. It was also found that non-coding RNA transcripts outnumber canonical protein-coding genes. This mindboggling discovery prompted a surge in non-codin...
non-coding RNA是指各种不翻译成蛋白质的RNA分子,包括rRNA、tRNA、snRNA、siRNA和miRNA等。这些RNA从基因组转录而来,在RNA水平直接行使功能。 根据题目提供的信息,非编码RNA的核心定义为“不翻译成蛋白质,直接从RNA分子发挥功能”。列举的rRNA(核糖体RNA,参与蛋白合成支架)、tRNA(转运RNA,负责氨基酸转运)、snRNA(小核...
1.和siRNA一样装载成RISC(RNA induced silencing complex , RISC;沉默复合物)后互补配对的mRNA降解; 2.miRNA可抑制mRNA的翻译,降低靶基因的蛋白质水平但不影响期mRNA的水平。 三、lncRNA(long non-coding RNA) IncRNA的长度一般大于200bp。根据基因组位点或相关的DNA特征,可以进一步进行分类(图4): 图4 长链非...
读懂非编码RNA(ncRNA) 在真核生物基因组中,大约 90%的基因是转录基因,在这些转录基因中只有1-2%编码蛋白质,其他大多数转录为非编码RNA。非编码RNA (non-coding RNA, ncRNA)是指由 基因组转录而成的不编码蛋白… 生命探索者 非编码RNA干货 | ncRNA的调控概述 在上一系列的干货分享中,我们介绍了细胞培养相关知...
简述非编码RNA(non-coding RNA)的种类、结构特点及其主要功能。非编码RNA的种类结构和功能1 tRNA 转运RNA(transfer RNA,tRNA)
non-coding rna名词解释 非编码RNA(non-coding RNA,ncRNA)指的是在转录成RNA时不被翻译成蛋白质的RNA分子。与编码蛋白质的mRNA相比,ncRNA的功能非常多样,包括调控基因表达、RNA的剪接和稳定性、染色体转录后修饰等。非编码RNA是生物学研究领域中的一个热门话题,对于揭示细胞及多细胞生命现象的本质具有重要意义。
Non-codingRNAsare those RNAs that do not undergo the translation process ofprotein synthesis. Non-codingRNA(ncRNA) molecules are transcribed from more than 70% of the genome. More than 40 different types ofnon-coding RNAsare known and they are mostlyribosomal RNAs(rRNAs), transfer RNAs (tRNAs...
Non-coding RNA Researchaims to publish high quality research and review articles on the mechanistic role of non-coding RNAs in all human diseases. This interdisciplinary journal will welcome research dealing with all aspects of non-coding RNAs-their biogenesis, regulation and role in disease … ...
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