间充质干细胞源性外泌体(MSC-derived exosomes)是MSCs旁分泌作用的主要物质,也是目前研究和应用最广泛的外泌体之一。其包含与MSCs类似治疗性的生长因子及mRNA等生物活性物质,具有组织修复、免疫调节等疗效,同时又具备独特的优势,如:无自我复制能力,所以没有致瘤性;纳米级体积避免毛细血管截留,可以通过血脑屏障到达中...
Concise Review: MSC-Derived Exosomes for Cell-Free Therapy. Stem Cells 2017, 35, 851-858. [CrossRef] [PubMed]D.G. Phinney, M.F. Pittenger, Concise review: MSC-derived exosomes for cell-free therapy, Stem Cells 35 (2017) 851-858....
MSC-derived exosomes protect auditory hair cells from neomycin-induced damage via autophagy regulation Huan Liu, Huijuan Kuang, Yiru Wang, Lili Bao, Wanxin Cao, Lu Yu, Meihao Qi, Renfeng Wang, Xiaoshan Yang, Qingyuan Ye, Feng Ding, Lili Ren, Siying Liu, Furong Ma & Sh...
www.nature.com/cddis ARTICLE OPEN HucMSC-derived exosomes delivered BECN1 induces ferroptosis of hepatic stellate cells via regulating the xCT/GPX4 axis Youwen Tan1,4, Yan Huang2,3,4, Rong Mei2, Fei Mao 2, Dakai Yang2, Jinwen Liu2, Wenrong Xu2, Hui Qian2 ✉ and Yongmin Yan 1,2 ...
Furthermore, it might be possible to harvest exosomes from supernatants of immortalized MSC cell lines, which otherwise could not be used for cellular therapies. Given the history of a therapy-refractory GvHD patient (Supplementary Figure S1), we decided to treat the patient in an individual ...
2 MSC-derived exosomes 132018-02 3 2018.1.15老人与海 282018-01 4 Turtle 42018-01 5 Extracellular vesicles 112018-01 6 牙周病 152018-01 7 2018.01.04老人与海 132018-01 8 2017.12.31弗兰肯斯坦2 132017-12 9 2017.12.31弗兰肯斯坦 82017-12 10 2017.12.29弗兰肯斯坦 82017-12 查看更多 ...
MSCs and MSC-derived exosomes: focus on wound healing Biomimetic scaffolds for delivery of MSCs and MSC-derived exosomes Biomimetic scaffolds combination with MSCs or MSC-derived exosomes: role in wound healing Future prospective Conclusion Data availability Abbreviations References Acknowledgements Funding Au...
CGMP-Compliant Isolation and Development of MSC-Derived Exosomes Learn More Experience an Innovative Biotechnology Product Explore the Benefits of MSC-Derived Exosomes at Kimera Labs At Kimera Labs, we’re committed to providing cutting-edge clinical solutions to healthcare providers through up-to-date...
CGMP-Compliant Isolation and Development of MSC-Derived Exosomes Learn More Experience an Innovative Biotechnology Product Explore the Benefits of MSC-Derived Exosomes at Kimera Labs At Kimera Labs, we’re committed to providing cutting-edge clinical solutions to healthcare providers through up-to-date...
While many studies describe exosomes as deriving from multivesicular bodies, solid evidence about the origin of EVs is often lacking. Extracellular vesicles represent an important portion of the cell secretome. Their numerous properties can be used for diagnostic, prognostic, and therapeutic uses, so ...