4.外泌体糖尿病的免疫调节作用 伊朗德黑兰伊斯兰阿萨德大学的科学家在国际科技学术期刊Cell Biochem. 上发表的标题为Immunomodulatory effects of mesenchymal stem cell-derived exosomes on experimental type-1 autoimmune diabetes(间充质干细胞衍...
Several recent results, including ours, support that exosomes, and their microRNA (miR) cargo, underlie at least some of these paracrine effects. Our objective was to test the hypothesis that MSC-derived exosomes from non-treated MSC can mediate cardioprotection via specific miR cargo. To test ...
Optimal-Pharmaceutical Grade Exosomes, Isolated Stemcell Exosomes Learn More INNOVATION Facilitating Clinical Breakthroughs for the Use of MSC-Derived Exosome in Therapeutics and Diagnostics Learn More REGULATION CGMP-Compliant Isolation and Development of MSC-Derived Exosomes ...
Kimera® Labs Receives FDA Phase I/IIa IND Clearance For Its MSC Exosomes Human Study Read More » May 16, 2023 The Utilization of Human Placental Mesenchymal Stem Cell Derived Exosomes in Aging Skin: An Investigational Pilot Study Read More » ...
✦ ✦ ✦ 往期回顾 参考文献: Lotfy, A., AboQuella, N.M. & Wang, H. Mesenchymal stromal/stem cell (MSC)-derived exosomes in clinical trials. Stem Cell Res Ther 14, 66 (2023). https://doi.org/10.1186/s13287-023-03287-7.
近期,浙江大学医学院附属第一医院传染病重症诊治全国重点实验室李兰娟院士/曹红翠教授团队在Asian Journal of Pharmaceutical Sciences(JCR:Q1, IF:10.2)上发表了题为“MSC-derived exosomes attenuate hepatic fibrosis in primary sclerosing cholangitis through inhibition of Th17 differentiation”的原创性研究论文。该研究...
1、Mesenchymal stromal/stem cell (MSC)-derived exosomes in clinical trials https://stemcellres.biomedcentral.com/articles/10.1186/s13287-023-03287-7 2、Nojehdehi, S.; Soudi, S.; Hesampour, A.; Rasouli, S.; Soleimani, M.; Hashemi, S.M. Immunomodulatory effects of mesenchymal stem cell...
间充质干细胞源性外泌体(MSC-derived exosomes)是MSCs旁分泌作用的主要物质,也是目前研究和应用最广泛的外泌体之一。其包含与MSCs类似治疗性的生长因子及mRNA等生物活性物质,具有组织修复、免疫调节等疗效,同时又具备独特的优势,如:无自我复制能力,所以没有致瘤性;纳米级体积避免毛细血管截留,可以通过血脑屏障到达中...
【2】Cui L, Luo W, Jiang W, Li H, Xu J, Liu X, Wang B, Wang J, Chen G (2022) Human umbilical cord mesenchymal stem cell-derived exosomes promote neurological function recovery in rat after traumatic brain injury by inhibiting the activation of microglia and astrocyte.【3】Ying Ge,...
【2】Cui L, Luo W, Jiang W, Li H, Xu J, Liu X, Wang B, Wang J, Chen G (2022) Human umbilical cord mesenchymal stem cell-derived exosomes promote neurological function recovery in rat after traumatic brain injury by inhibiting the activation of microglia and astrocyte. ...