Khoury, "Mesenchymal stem cell-derived exosomes from different sources selectively promote neuritic outgrowth," Neuroscience, vol. 320, pp. 129-139, 2016.Lopez-Verrilli MA, Caviedes A, Cabrera A, Sandoval S, Wyneken U, Khoury M. Mesenchymal stem cell-derived exosomes from different sources ...
A large number of studies have found that exosomes derived from different cells are rich in neuroprotective and immunomodulatory miRNAs, nerve growth factors, and anti-inflammatory factors, which can reduce neuroinflammation, promote new blood vessel formation, induce neurogenesis, reduce neuronal apoptosis...
Current researches have indicated that exosomes derived from different sources are a new remedial tool. MSCs-derived exosomes The MSCs-derived exosomes have been assayed in disease models like diabetes mellitus, renal disease, dermatological, gastrointestinal, hepatic, musculoskeletal, neurological, cardiovasc...
In conclusion, the inherent tumor antigens endow tumor exosomes with advantages for antitumor vaccine. Nevertheless, tumor-derived exosomes, serving as therapeutic agents, are double-edged swords. There still exist multiple problems needed to be resolved, such as the immune cell suppression,188the esc...
Therefore, this review mainly describes the roles and mechanisms of exosomes from different sources, namely, MSCs and skin sources, in improving diabetic wound healing(Fig.3). A deeper understanding of therapeutic exosomes will yield promising candidates and perspectives for diabetic wound healing manage...
bioactive molecule encapsulation, and intercellular communication [3]. Exosomes from different cell death pathways play distinct roles; for example, those from apoptotic cells may activate immune responses [5], while those from necrotic or pyroptotic cells can induce immune cell death and amplify infl...
(REF). Recently, it’s been reported that exosomes from different sources can benefit wound healing including the remodeling phase. The production of type I collagen and elastin can be encouraged by exosomes produced from hUC-dMSCs [103]. Exosomes produced by human induced pluripotent stem cells...
The properties of NK cell-derived exosomes Like other immune cells, NK cells can also secrete exosomes with various cargo and affect the target cells (Fig.2). Exosomes from different sources have some common characteristics; for example, they contain multivesicular bodies associated proteins such as...
GMSC-derived exosomes exhibit comparable biological functions and therapeutic effects as GMSCs, thus representing a promising option for cell-free therapy [24]. Exosomes can reflect their cellular origin and the physiological state of the cells, therefore MSCs-Exos from different sources have different...
Exosomes derived from various sources including MSCs, keratinocytes, endothelial cells, immune cells, and several other body fluids can regulate wound healing [52]. Exosomes obtained from mesenchymal stem cells (MSCs-Exos) exhibit superior functionality and greater ease of handling compared to cell-...