Exosomes have a wide range of sources and distributions, diverse functions, and are closely related to their respective source cells. Different exosomes have different biological characteristics and can produce different effects due to factors such as their contents, tissue microenvironment, and receptor ...
Mesenchymal stem cell-derived exosomes from different sources selectively promote neuritic outgrowth. Neuroscience. 2016; 320:129-39.M. Lopez-Verrilli, A. Caviedes, A. Cabrera, S. Sandoval, U. Wyneken, and M. Khoury, "Mesenchymal stem cell-derived exosomes from different sources se...
A large number of studies have found that exosomes derived from different cells are rich in neuroprotective and immunomodulatory miRNAs, nerve growth factors, and anti-inflammatory factors, which can reduce neuroinflammation, promote new blood vessel formation, induce neurogenesis, reduce neuronal apoptosis...
Current researches have indicated that exosomes derived from different sources are a new remedial tool. MSCs-derived exosomes The MSCs-derived exosomes have been assayed in disease models like diabetes mellitus, renal disease, dermatological, gastrointestinal, hepatic, musculoskeletal, neurological, cardiovasc...
270 Additional research is needed to improve the therapeutic effects of exosomes derived from different sources. Nevertheless, there are also some challenges and problems in this field. There is still a lack of direct evidence that endogenous exosomes could transfer from one cell to another cell in...
3). Clarifying the intrinsic immunomodulatory capacity of exosomes derived from different cells and using exosomes as carriers to initiate anticancer immune responses or deliver anticancer drugs could help to further improve drug efficacy. Tumor-derived exosomes (TEXs) carry specific tumor antigens, ...
Therefore, this review mainly describes the roles and mechanisms of exosomes from different sources, namely, MSCs and skin sources, in improving diabetic wound healing(Fig.3). A deeper understanding of therapeutic exosomes will yield promising candidates and perspectives for diabetic wound healing manage...
(REF). Recently, it’s been reported that exosomes from different sources can benefit wound healing including the remodeling phase. The production of type I collagen and elastin can be encouraged by exosomes produced from hUC-dMSCs [103]. Exosomes produced by human induced pluripotent stem cells...
Exosomes can be used as biomarkers in ovarian cancer and utilized for treatment. A good understanding of their role in cancer development, eliminating exosomes, or inhibiting exosome uptake by recipient cells can improve therapeutic outcomes in ovarian cancer. Exosomes from different sources can deliver...
bioactive molecule encapsulation, and intercellular communication [3]. Exosomes from different cell death pathways play distinct roles; for example, those from apoptotic cells may activate immune responses [5], while those from necrotic or pyroptotic cells can induce immune cell death and amplify infl...