MHC Class II基因有许多别称,如HLA-D region(人类白细胞抗原-D区域)、Ia gene(Ia基因)等。这些别称来源于基因所在的位置和功能。在我国,MHC Class II基因的研究已取得丰硕成果,为免疫学、遗传学等领域的发展做出了巨大贡献。 【五、总结】 MHC Class II基因作为免疫系统中的关键分子,其研究不仅在基础科学领域具...
The origin of MHC class II gene polymorphism within the genus Mus. Nature 1988;332:651-54. [PubMed: 2895893]McConnell TJ, Talbot WS, McInode RA, Wakeland EK. 1988. The origin of MHC class II gene polymorphism within the genus Mus. Nat. 332:651-54...
This complex gene-expression profile is controlled almost exclusively by a single master regulatory factor, which is known as the class II transactivator. As we discuss here, differential activation of the three independent promoters that drive expression of the gene encoding the class II ...
CONCLUSIONS: The lack of induction of MHC class II genes in response to IFN-γ in trophoblast cells is caused neither by the absence of factors that bind class II promoters, nor by a lesion in the IFN-γ signaling pathway, but results from a specific inhibition of the CIITA gene. 展开 ...
货号MA5-16608 2 mL CNY5,654.00 查看价格 下单后预计有货时间 17-Jan-2025 数量 批量或定制请求 性能保障 说明书 实验方案 技术支持 产品信息 应用 建议稀释比 已发表文章 免疫组化(冰冻) (IHC (F)) Assay-dependent - 流式细胞分析 (Flow)
Isotype-specific regulation of MHC class II gene expression in human monocytes by exogenous and endogenous tumor necrosis factor 喜欢 0 阅读量: 22 作者:Marek,Jasiński,Jerzy,Wieckiewicz,Irena,Ruggiero,Anna,Pituch-NoworolskaMarek,Zembala 摘要: The control of expression of MHC class II molecules on...
提供的MHC Class II (I-A/I-E)单克隆抗体, 克隆号M5/114。15。2产品克隆号为M5/114。15。2,对应的亚型为IgG2b, kappa。该基因又称,全名为,对应Gene号为,其蛋白编号为。 应用类型 WB,IHC,Func,Flow Cyt 免疫原 Mouse MHC Class II (I-A/I-E)。
对上述单细胞 RNA 测序数据进行的基因组富集分析(Gene set enriched analysis,GSEA)显示,小鼠 Padi4 高的巨噬细胞表现出多种上调通路,包括肽基精氨酸修饰(GO: 0018195)、蛋白质瓜氨酸化(GO: 0018101)和蛋白-精氨酸脱亚胺酶活性(GO:0004668),以及几种下调途径,包括抗原加工和通过 MHC II 类(GO:0019886)、MHC ...
The majority of such clones expressed the T3++T8-T11++ phenotype and were directed at autologous class II MHC gene products found on B , macrophages and B lymphoblastoid as judged by their proliferative response to the latter. For this recognition, the clones employed a T3-Ti molecular complex...
We have studied the temporal variation (1999–2007) in the MHC class II DQA gene and 8 microsatellites across 8 cohorts in a population of brown hare (Lepus europaeus) from eastern Austria. Our results show no significant temporal changes in allele frequencies both in microsatellites and the DQA...