MHCIII类基因 MHCIII类基因是20074公布的免疫学名词。定义 位于MHCI和MHCII类基因区之间的一组基因。编码产物为某些血清补体成分，如人C2、Bf、C4A和C4B。出处 《免疫学名词》。
MHC分子高亲和力与抗原肽结合成为复合物,这是保证MHC分子有效提呈抗原 的重要前提。 MHC-I分子的肽槽由MHC-Ia链的 a1和 a2结构域组成,而MHC-II分子的肽 槽由MHC-IIa 链的 a1和MHC-IIb 链的 b1结构域组成。前者的两端处于封闭 状,而后者的两端则较为开放。MHC-I分子...
Gene-knockout mice carrying deletions of the corresponding mouse gene (C2ta) also show most features of the human disease. The highly regulated pattern of expression of the gene encoding CIITA dictates where, when and to what level MHC class II genes are expressed. Transcription of the gene ...
DNA ribotide and a corresponding amino acid sequence of the cobia MHC-II beta gene sequence are explained in SEQ ID NO.1. The acquisition of the gene not only lays the foundation for researching the function mechanism of the fish MHC-II beta molecules and the relation between the MHC-II ...
The sequences indicate that unlike the domestic fowl with its compact, gene-poor Mhc , the Mhc of the Darwin's Finches contains more than half a dozen of class II B loci alone. Roth the exon 2 and intron 2 sequences suggest that the genes at the different loci are closely related and...
CONCLUSIONS: The lack of induction of MHC class II genes in response to IFN-γ in trophoblast cells is caused neither by the absence of factors that bind class II promoters, nor by a lesion in the IFN-γ signaling pathway, but results from a specific inhibition of the CIITA gene. 展开 ...
提供的MHC Class II (I-A/I-E)单克隆抗体, 克隆号M5/114。15。2产品克隆号为M5/114。15。2,对应的亚型为IgG2b, kappa。该基因又称,全名为,对应Gene号为,其蛋白编号为。 应用类型 WB,IHC,Func,Flow Cyt 免疫原 Mouse MHC Class II (I-A/I-E)。
(1)经典MHC基因经典MHCI类相关基因HLA-A、B、C、经典MHCII类相关基因HLA-DP、DQ、DR(2)免疫功能相关基因编码补体成分的基因C2、C4A、C4B、Bf(III类区),抗原加工递呈相关基因LMP、TAP、HLA-DM、HLA-DO(II类区),非经典I类基因HLA-E、F、G(I类区),炎症相关基因TNF、HSP70(III类区),基因座位genelocus,指...
经典MHC基因 经典MHC基因是2007年公布的免疫学名词。定义 具有高度多态性的MHC基因。其编码产物直接参与抗原提呈并决定个体组织相容性。在人类，HLA-A、HLA-B、HLA-C(HLA-Ia)属经典的HLAI类基因；HLA-DR、HLA-DQ、HLA-DP属经典的HLAII类基因。出处 《免疫学名词》。