可能您是非常英俊的,可能您是非常逗人喜爱的,我可能爱以您。 [translate] aSo, I'm glad to meet you, 如此,我是高兴遇见您, [translate] aThe P53 tumor suppressor gene product is a transcription factor involved in DNA repair. P53肿瘤遏抑器基因产品是在脱氧核糖核酸修理介入的副本因素。 [translate] ...
a工序流程图 Working procedure flow chart [translate] aThe P53 tumor suppressor gene product is a transcription factor involved in DNA repair. P53肿瘤遏抑器基因产品是在脱氧核糖核酸修理介入的副本因素。 [translate] 英语翻译 日语翻译 韩语翻译 德语翻译 法语翻译 俄语翻译 阿拉伯语翻译 西班牙语翻译 葡萄牙...
Transcription regulates axon outgrowth and regeneration. However, to date, no transcription complexes have been shown to control axon outgrowth and regeneration by regulating axon growth genes. Here, we report that the tumor suppressor p53 and its acetyltransferases CBP/p300 form a transcriptional complex...
p53 is a transcription factor also called the "cellular gatekeeper of genome" because it can induce cell cycle arrest in G1, apoptosis or affect DNA replication in response to DNA damage. Wild type p53 is localised in both the cytoplasm and nucleus of first trimester trophoblastic cells (CTB)...
P53 is a transcription factor that can cause cells to be eliminated by apoptosis or senescent-like arrest upon its activation by irreparable genetic damage, excessively expressed oncogenes, or a broad spectrum of other stresses. As P53 executes life and death decisions, its activity must be string...
p53 exerts its tumor-suppressive function mainly as a transcription factor. Many p53 target genes have been shown to regulate cellular processes involved in the prevention of tumorigenesis, such as the induction of cell cycle arrest, apoptosis and DNA repair [3]. In addition, p53 acts as a ...
Together, our results put forward the hypothesis that the absence of p53 may determine a higher chemotherapeutic index for 5-aza-dC. 展开 关键词: ONC oncogenes cancer apoptosis tumor suppressor genes tumor viruses molecular oncology cell cycle growth factors growth factor receptors ...
(PyLT), a potent viral oncogene. We propose that a subset of these alterations in gene expression may be related to the early events that contribute to carcinogenesis. The proposed tumor suppressor Necdin, known to be regulated by p53, was within a group of genes that was consistently up...
The tumor suppressor p53 is a transcription factor that contains 393 amino acids with two distinct nucleic acid-binding domains: the central DNA-binding core domain and a second nucleic acid-binding domain at the C-terminal (30 amino acids in size). The core domain is responsible for binding ...
Boggs K, Reisman D., Increased p53 transcription prior to DNA synthesis is regulated through a novel regulatory element within the p53 promoter. Oncogene, 2006. 25(4): 555-65. :Boggs K, Reisman D. Increased p53 transcription prior to DNA synthesis is regulated through a novel regulatory ele...