1 近日,我校海洋学院陈新华团队的研究解析了大黄鱼I型干扰素IFNi的高分辨(1.39 Å)晶体结构,并揭示了IFNi与受体结合的详细机制。研究结果以题为“Molecular and Structural Basis of Receptor Binding and Signaling of a Fish Type I ...
In this study, we sought to probe the effect of ionizing radiation on activity of cGAS-STING-IFNI pathway in normoxic or hypoxic glioma cells and explore a more effective method to activate the signaling pathway, thereby activating the anti-tumor immune response and improving the therapeutic ...
近日,福建农林大学海洋学院陈新华团队的研究解析了大黄鱼I型干扰素IFNi的高分辨(1.39 Å)晶体结构,并揭示了IFNi与受体结合的详细机制。研究结果以题为“Molecular and Structural Basis of Receptor Binding and Signaling of a Fish Type I IFN with Three Disulfide Bonds”的论文发表于美国免疫学家协会的旗舰期刊...
近日,福建农林大学海洋学院陈新华团队的研究解析了大黄鱼I型干扰素IFNi的高分辨(1.39 Å)晶体结构,并揭示了IFNi与受体结合的详细机制。研究结果以题为“Molecular and Structural Basis of Receptor Binding and Signaling of a Fish Type ...
However, the overactivation of this signaling pathway leads to fatal immune disorders and contributes to the progression of many human inflammatory diseases. Therefore, optimal activation of this pathway is crucial for the elimination of invading pathogens and the maintenance of immune homeostasis. In ...
However, the overactivation of this signaling pathway leads to fatal immune disorders and contributes to the progression of many human inflammatory diseases. Therefore, optimal activation of this pathway is crucial for the elimination of invading pathogens and the maintenance of immune homeostasis. In ...
However, the overactivation of this signaling pathway leads to fatal immune disorders and contributes to the progression of many human inflammatory diseases. Therefore, optimal activation of this pathway is crucial for the elimination of invading pathogens and the maintenance of immune homeostasis. In ...