[5].Scott, Fergus Perry, et al. "Factors affecting cell-free DNA fetal fraction and the consequences for test accuracy." The Journal of Maternal-Fetal & Neonatal Medicine 31.14 (2018): 1865-1872. [6].Dugoff, Lorraine, et al. "Cell-fre...
无创产前筛查 (Noninvasive Prenatal Screening,NIPS) 是基于孕妇外周血中胎儿游离DNA (cell-free DNA,cfDNA) 来提示有关胎儿染色体异常信息的检测方法。母体内胎源cfDNA的百分比,即胎儿游离DNA片段浓度 (Fetal Fraction,FF) 通常在4%~30%,游离胎儿DNA浓度是否充足对NIPS的灵敏性和特异性具有关键作用。一些体重指数(BM...
cell free DNAfirst trimesterhypertensive disorderspreeclampsiaTo investigate whether first-trimester maternal plasma fetal fraction is altered in women that subsequently develop preeclampsia (PE) or gestational hypertension (GH) and to examine its potential value in improving the performance of screening for...
The fetal fraction, or percentage of total cell-free DNA (cfDNA) in a sample derived from the fetus, can impact NIPT results and profitability.
Fetal Fraction in Maternal Plasma Cell-Free DNA at 11–13 Weeks' Gestation: Effect of Maternal and Fetal Factors Objective: It was the aim of this study to examine the possible effects of maternal and fetal characteristics on the fetal fraction in maternal plasma cell... Ghalia,Ashoor,Leona,...
不好。对于我国GDP9.1%的增速来看，快速的经济增长是存在很多问题的，比如环境污染，浪费严重，贫富差距加大等等，而最主要的消极因素是经济增长效率低下，出现大量低水平重复建设。出现严重的产能过剩。
To determine the association between cell-free DNA fetal fraction (cffDNA) and various prenatal characters to better guide the clinical application of noninvasive prenatal screening (NIPS), a retrospective cohort study of 27,793 women with singleton pregnancies was conducted. Results indicated that no...
Cell-free fetal DNA fraction (FF) in maternal plasma is a key parameter affecting the performance of noninvasive prenatal testing (NIPT). Accurate quantitation of FF plays a pivotal role in these tests. However, there are few methods that could determine FF with high accuracy using shallow‐dep...
Objective: It was the aim of this study to examine the possible effects of maternal and fetal characteristics on the fetal fraction in maternal plasma cell-free DNA (cfDNA) at 11–13 weeks’ gestation. Methods: In a nested case-control study, cfDNA was extracted from maternal...
Fetal cell-free DNA A major breakthrough in the approach to accurate, noninvasive prenatal screening occurred after the discovery of fetal cfDNA in the maternal serum in 1997.10 Circulating cfDNA fragments are short fragments of DNA found in the blood. During pregnancy, there are cfDNA fragments...