cell‐free DNAfetal genotypingRhDhaemolytic disease of the fetus and newbornKELRh prophylaxisIn transfusion medicine and clinical immunology, cell‐free fetal DNA (cffDNA) is analysed from maternal plasma of pregnant women to predict fetal blood groups with the purpose of (1) assessing the risk ...
[5].Scott, Fergus Perry, et al. "Factors affecting cell-free DNA fetal fraction and the consequences for test accuracy." The Journal of Maternal-Fetal & Neonatal Medicine 31.14 (2018): 1865-1872. [6].Dugoff, Lorraine, et al. "Cell-fre...
Quantitative study of cell-free fetal DNA-SRY gene in preterm labour maternal plasma 早产孕妇血浆中游离胎儿DNA-SRY基因片段的定量检测 www.ilib.cn3. The value of the detection of cell-free fetal DNA in maternal plasma in the preeclampsia women using fluorescent quantitative PCR 荧光定量PCR检测孕妇...
aeinem Arbeitspensum von 100% 工作负担100%[translate] anotificación 通知[translate] aFetal cells and cell-free fetal DNA in maternal blood: new insights into pre-eclampsia 胎儿细胞和无细胞胎儿脱氧核糖核酸在母亲血液: 新的洞察到子痫前期里[translate]...
Fetal Fraction in Maternal Plasma Cell-Free DNA at 11–13 Weeks' Gestation: Effect of Maternal and Fetal Factors Objective: It was the aim of this study to examine the possible effects of maternal and fetal characteristics on the fetal fraction in maternal plasma cell... Ghalia,Ashoor,Leona,...
Fetal cell-free DNA A major breakthrough in the approach to accurate, noninvasive prenatal screening occurred after the discovery of fetal cfDNA in the maternal serum in 1997.10 Circulating cfDNA fragments are short fragments of DNA found in the blood. During pregnancy, there are cfDNA fragments...
Current non-invasive prenatal screening (NIPS) analyzes circulating fetal cell-free DNA (cfDNA) in maternal peripheral blood for selected aneuploidies or microdeletion/duplication syndromes. Many genetic disorders are refractory to NIPS largely because t
The fetal fraction, or percentage of total cell-free DNA (cfDNA) in a sample derived from the fetus, can impact NIPT results and profitability.
Targeted fetal cell‐free DNA screening for aneuploidies in 4,594 pregnancies: Single center studycfDNA screeningNIPSNIPTBackgroundNext‐generation sequencing (NGS) and discovery of fetal cell‐free DNA (cfDNA) in the maternal circulation render possible prenatal screening for trisomy 21 (Down syndrome...
无创产前筛查 (Noninvasive Prenatal Screening,NIPS) 是基于孕妇外周血中胎儿游离DNA (cell-free DNA,cfDNA) 来提示有关胎儿染色体异常信息的检测方法。母体内胎源cfDNA的百分比,即胎儿游离DNA片段浓度 (Fetal Fraction,FF) 通常在4%~30%,游离胎儿DNA浓度是否充足对NIPS的灵敏性和特异性具有关键作用。一些体重指数(BM...