alzheimer's diseaseapolipoprotein edementiaA 64-year-old man underwent APOE ?4 allele testing for 3 years of forgetfulness and word-finding difficulties and a family history of early-onset dementia, with results positive for genotypes 3 and 4 indicating "with high specificity, that Alzheimer's ...
Alzheimer's disease: a re-examination of the amyloid hypothesis the disease, whereas the 4 allele of the apolipoprotein E (apoE) gene has been shown to be a significant risk factor for the late onset forms of AD... Rachael L. Neve a,Nikolaos K. Robakis b - 《Trends in Neurosciences》...
Possessing an apolipoprotein E (APOE) epsilon 4 allele, advanced age and smoking are risk factors for Alzheimer's disease and cognitive decline. Deficits in cognitive function also increase risk for smoking relapse. Data from 917 adult smokers of European ancestry were pooled across three randomized...
APOE e4, an Alzheimer's Disease Susceptibility Allele, Predicts Relapse among Older Treatment-seeking Smokers Rebecca L. Ashare*, Jason Karlawish, E. Paul Wileyto, Angela Pinto, Caryn Lerman University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania Background: Possessing an ...
The influence of parental history of Alzheimer's disease and apolipoprotein E epsilon4 on the BOLD signal during recognition memory. First-degree family history (FH) of sporadic Alzheimer's disease and the apolipoprotein E 蔚4 allele (APOE4) are risk factors for Alzheimer's disease that ... ...
Context.—Although the association between Alzheimer disease (AD) and the apolipoprotein E ∊4 (APOE-∊4) allele has been confirmed worldwide, it appears
ApoE epsilon(4) Allele Related Alterations in Hippocampal Connectivity in Early Alzheimer's Disease Support Memory Performance Background: Whether the presence of the Apolipoprotein E epsilon(4) allele modulates hippocampal connectivity networks in abnormal ageing has yet to be ful... De Marco, Matteo...
APOEe4 is well‐established genetic risk factor for late onset Alzheimer's disease (LOAD). It has been demonstrated that DNA methylation plays an important role in controlling the levels of APOEe4 expression. Furthermore, the differential methylation levels were reported between disease‐ and nave...
Malkki H. Alzheimer disease: effects of the APOE ε4 allele on brain development. Nat Rev Neurol. 2014;10(1):4.Malkki, H. Alzheimer disease: Effects of the APOE epsilon4 allele on brain development. Nat. Rev. Neurol. 2014, 10, 4....
Interactive effects of physical activity and APOE-ε4 on white matter tract diffusivity in healthy elders - ScienceDirect Older adult apolipoprotein-E epsilon 4 (APOE-ε4) allele carriers vary considerably in the expression of clinical symptoms of Alzheimer's disease (AD), sug... J. Carson Smit...