To ascertain the possible physical between bindarit and FABP4, competitive binding assays were performed, in which increasing concentrations of bindarit were used to displace radiolabeled fatty acids bound to FABP4. Bindarit was shown to be able to fully displace both [3H]-oleic acid and [3H]-ar...
3-Amino-2-hydroxypropoxyphenyl derivs. of formula (I) and their acid-addn. salts are new: (where A is linear 2-4C alkylene or alkenylene; n = 1-3; R is M, F, Cl or Br; R1 is CR2R3R4 and R5 is H, or NR1R5 is 2,2,6, 6-tetramethyl-piperidino, 2,2,5,5-tetramethyl...