A mean coverage of 30X was obtained when the sequencing reads were mapped to a human reference genome. Following further bioinformatic processing, allele calling, quality checks and filtering to match the genealogy DNA database SNPs, genotypes for approximately one million SNPs were established. The...
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the genome of which was sequenced to produce the first reference assembly, including the mitochondrial genome7. To obtain the present new reference assembly, we used these recent data based on the Illumina shotgun-sequencing technology and the present new...
Switzerland), utilizing the Solexa technology according to the manufacturer's recommendations (Illumina). The whole-genome sequencing was performed in 2007 on a Genome Analyzer "classic" instrument with sequencing kits version 1 and base calling on ...
Whole genome sequencing (WGS) is becoming the preferred method for molecular genetic diagnosis of rare and unknown diseases and for identification of actionable cancer drivers. Compared to other molecular genetic methods, WGS captures most genomic variat
Whole genome sequencing (WGS) refers to the process of presenting the full sequence of DNA, referring to the sequence of the four letters (A, C, G, and T) which constitute the DNA molecule, containing the hereditary material of all types of life. WGS is typically based on the use of ...
whole genome re-sequencing was conducted and genome-wide single nucleotide polymorphisms (SNPs) of 300 domestic chickens (including 240 domestic chickens from eight Guizhou local chicken breeds, and 60 commercial chickens from two common broiler and layer breeds) were generated. The genomic data of ...
Numerous viral sequences have been reported in the whole-genome sequencing (WGS) data of human blood. However, it is not clear to what degree the virus-mappable reads represent true viral sequences rather than random-mapping or noise originating from sample preparation, sequencing processes, or ...
The Thoroughbred breed was formed by crossing Oriental horse breeds and British native horses and is currently used in horseracing worldwide. In this study, we constructed a single-nucleotide variant (SNV) database using data from 101 Thoroughbred racehorses. Whole genome sequencing (WGS) revealed...
Until recently, the scope of sequencing projects was limited by the cost and throughput of Sanger sequencing. The raw data for the three billion base (3 gigabase (Gb)) human genome sequence, completed in 2004 (ref. 1), was generated over several years for ∼$300 million using several ...