Robin Gasser and his colleagues report the whole-genome sequence of Schistosoma haematobium. They include comparisons to the genome sequences of S. mansoni and S. japonicum, the two other species that cause schistosomiasis in humans. Schistosomiasis is a
Amalio Telenti, Craig Venter and colleagues report common, low-frequency and rare variants associated with blood metabolite levels using whole-genome sequencing and comprehensive metabolite profiling in 1,960 individuals. They identify 246 metabolites wh
Currently next generation sequencing facilitates SNP discovery and allows deeper analysis of genome variation [1, 2]. In plants, SNP discovery has been performed either from RNA-Seq experiments [3, 4] or whole genome resequencing. Millions of polymorphisms have thus been discovered in Arabidopsis [...
Cultivated peanut (Arachis hypogaea L.) is a widely grown oilseed crop worldwide; however, the events leading to its origin and diversification are not fully understood. Here by combining chloroplast and whole-genome sequence data from a large germplasm
whole genome sequencingabnormal development of the neural tubecloacaRubinstein-Taybi syndromeAuthor information: (1)Royal Children's Hospital, Murdoch Childrens Research Institute, Melbourne, Victoria, Australia; Department of Paediatrics, University of Melbourne, Melbourne, Victoria, Australia....
Hericium erinaceus Whole genome sequencing CAZymes Transcription factors Microsatellite markers database 1. Introduction Mushrooms have been consumed for their nutritional values and health-promoting properties for millennia [1]. Global mushroom production has increased rapidly last decades and is expected to...
(2019).QTG-seqacceleratesQTLfinemappingthroughQTLpartitioningandwhole-genomesequencingonbulkedsegregantsamples.Mol.Plant.doi:https://doi/10.1016/j.molp.2018.12.018.ThisisaPDFfileofanuneditedmanuscriptthathasbeenacceptedforpublication.Asaservicetoourcustomersweareprovidingthisearlyversionofthemanuscript.The...
The cost of Whole Genome Sequencing (WGS) has decreased tremendously in recent years due to advances in next-generation sequencing technologies. Nevertheless, the cost of carrying out large-scale cohort studies using WGS is still daunting. Past simulation studies with coverage at ~2x have shown pro...
View PDFHighlights Summary The use of two kinase inhibitors (2i) enables derivation of mouse embryonic stem cells (ESCs) in the pluripotent ground state. Using whole-genome bisulfite sequencing (WGBS), we show that male 2i ESCs are globally hypomethylated compared to conventional ESCs maintained ...
Whole-genome sequencing has proven valuable and critical for refining the phylogenetic positions of a series of rhizobial strains [47]. In this study, we sequenced, assembled, and annotated theM. huakuaii7653R genome. We used this genome sequence to examine the phylogenetic position of MAFF303099...