Now That Whole Genome Sequencing Has Arrived, What Does the Data Really Tell Us?Lampel, Keith
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The finished version of the human genome sequence was published in April 2003. This version, which is available to the public, provides nearly all the information needed to do research on the whole human genome, which in turn enables us to better understand the genetic...
all protein coding genes (exome) or the entire genome (whole genome sequencing, WGS), providing a complete survey of a person’s genetic make-up. For nearly two decades, geneticists have been comparing genomes, searching for the differences that might explain why only some people develop...
Epidemiologic Research's 46th Annual Meeting in Boston, Massachusetts, entitled, “What Is the Role of Epidemiology in the Era of Molecular Biology and ... Kuller,H Lewis,Bracken,... - 《American Journal of Epidemiology》 被引量: 42发表: 2013年 The use of whole-genome sequencing for molecu...
This bias does not negate the use of whole-genome regression models as predictive machines; however, our results indicate that caution is needed when using marker-based regressions for inferences about population parameters such as the genomic heritability. 展开 ...
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off-target sites, unintended mutations were detected. Only a few studies conducted off-target analyses using unbiased detection methods (e.g. whole genome sequencing). No off-target effects that could be correlated to the genome-editing process were identified in these studies....
The complete genomic sequences of five microbes were reported. Approaches to using data from completely sequenced microbial genomes in phylogenetic studies are being explored, as is the application of microarrays to whole genome expression analysis. 展开 关键词:...
Whole genome sequencing is a laboratory process that examines a person's DNA makeup in order to provide information about the risk for developing diseases in the future, as well as to diagnose active symptoms or diseases. Currently, the technology is most commonly used to find a medical cause...