whole-genome sequencing (WGS) or whole-exome sequencing (WES), especially disease family-based WGS or WES, provides an elegant platform to seek rare susceptibility or pathogenic variants16,17,18. Such studies, however, have not yet been reported in the field of rosacea. ...
sectioned by a cryostat, and stained with hematoxylin and eosin. We performed macrodissection to enrich the tumor fraction relative to the dominant stromal component and other normal cells. DNA was extracted using a general protocol for genome sequencing. Preparation of ...
33,34,35] and undiagnosed diseases [36] and identify actionable cancer drivers and signatures. The different clinical applications and the type of analyses that are implicated in the diagnostics are shown in Fig.2. There are several reasons why whole-genome sequencing (WGS) is becoming the prefe...
The whole-genome resequencing data was generated for the samples from 36 wild mice by Illumina technology. Approximately 1.4 Tb data was acquired. Raw sequencing data for the 36 wild mice ranged from 24.4 to 54.3 Gb (Additional file1: Table S3). After mapping to the mouse reference genome (...
WES: Whole-exome sequencing WGS: Whole-genome sequencing References Naghavi M, Abajobir AA, Abbafati C, Abbas KM, Abd-Allah F, Abera SF, et al. Global, regional, and national age-sex specific mortality for 264 causes of death, 1980–2016: a systematic analysis for the Global Burden ...
To demonstrate how you can quickly apply HipSTR to whole-genome sequencing datasets, we've built a simpletutorial. In less than 10 minutes, this tutorial will teach you how to genotype ~600 STRs in a deeply sequenced trio of individuals and inspect the results. ...
Ming Li, Ruiqiang Li and colleagues report the whole-genome sequencing of a male golden snub-nosed monkey, Rhinopithecus roxellana, as well as its relatives Rhinopithecus bieti, Rhinopithecus brelichi and Rhinopithecus strykeri. Their analysis provides i
Genome Medicine(2024) Task design for crowdsourced glioma cell annotation in microscopy images Svea Schwarze Nadine S. Schaadt Friedrich Feuerhake Scientific Reports(2024) Multiplex protein imaging in tumour biology Natalie de Souza Shan Zhao
To demonstrate how you can quickly apply HipSTR to whole-genome sequencing datasets, we've built a simple tutorial. In less than 10 minutes, this tutorial will teach you how to genotype ~600 STRs in a deeply sequenced trio of individuals and inspect the results. In-depth Usage HipSTR has ...
Ultra-Rapid whole genome nanopore sequencing pipeline a. Base calling and Alignment Software: Guppy v4.2.2 (Commercial software from Oxford Nanopore Technologies) Minimap2 v2.17-r974 b.1. Small Variant Calling Software: PEPPER v0.5 (Docker image - kishwars/pepper_deepvariant:test-v0.5) Margin (...