doi:10.1515/labmed-2014-0025Klein, Hanns-GeorgBauer, PeterHambuch, TinaDe Gruyter《Laboratoriumsmedizin-journal of Laboratory Medicine》Klein HG, Bauer P, Hambuch T. Whole genome sequencing (WGS), whole exome sequencing (WES) and clinical exome sequencing (CES) in patient care. Laboratoriums...
8,9. Whole-genome sequencing (WGS) is a powerful technology for investigations of alterations in intronic and intergenic regions as well as in the exome, and provides an opportunity to delineate the complete MSs imprinted
but whole-genome sequencing (WGS) was conducted on only 11 tumors9. Results from this study suggested that amplifications ofTBXT(encoding brachyury), homozygous deletion ofCDKN2A, and mutations in SWI/SNF (SWItch/Sucrose Non-Fermentable) complex genes (PBRM1,...
Whole-genome sequencing (WGS) of GBM tumors has highlighted the importance of TERT promoter mutations in the development of the disease [9] and has been instrumental in improved understanding of clonal and sub-clonal evolution for GBM recurrences [10]. Because the absolute majority of mutations in...
We examined the feasibility of using whole-genome sequencing (WGS) data to design tumour-specific polymerase chain reaction (PCR)-based MRD tests (WGS-MRD) in 18 children with high-risk relapsed cancer, including ALL, high-risk neuroblastoma (HR-NB) and Ewing sarcoma (EWS) (n = 6 eac...
Analysis and Annotation of Whole-Genome or Whole-Exome Sequencing-Derived Variants for Clinical Diagnosis. 2013:, 9.24.1-9.24.24. /... EA Worthey - 《Current Protocols in Human Genetics》 被引量: 27发表: 2013年 Analysis and Annotation of Whole-Genome or Whole-Exome Sequencing-Derived ...
Whole genome sequencing has gone to the dogs.doi:10.1038/s41684-019-0315-9EllenLabAnimalPLabAnimalNeffLabAnimalPubmedLab animal
Wang,Lotus - 《Lab Animal》 被引量: 10发表: 2005年 DNA identification methods for isolated strain of ectomycorrhizal, mushrooms Recent methods of DNA identification developed both at home and abroad were reviewed for determining isolates true or false of ectomycorrhizal mushrooms. D Zeng - 《Journal...
Briefly, sequencing reads were trimmed by Trimmomatic (v0.32)37 to remove short read pairs with at least one end <36 bp. Reads were aligned to the hg19 reference genome using Novoalign software (v3.00.05) (http://www.novocraft.com). The alignments were refined by removing duplicate ...
Genome Sequence Analysis of the 10 Clinical Isolates The basic whole genome sequencing statistics are shown in Table 2. The mapped depth ranged between 70 × and 730 ×, and the percent of the reference genome covered was 99.97%-99.99%. Genome sequence analysis of the 10 clinical strains rev...