Whole genome sequencing (WGS) is the comprehensive read and analysis of an entire genome, including non-coding regions of the genome.
Whole-genome sequencing delivers a comprehensive view, ideal for discovery applications. Newer genome sequencers perform WGS more rapidly than ever.
news.medlive.cn|基于5个网页 3. 全基因组测序技术 全基因组测序技术(whole-genome sequencing)在临床上的首次亮相就显示出它有多么的与众不同。Cancel Reply 全基因组 … www.lifeomics.com|基于2个网页
Whole-genome sequencing is suitable for the study of disease-specific genomic abnormalities from cfDNA. TheInvitrogen Collibri PS DNA Library Prep Kit for Illumina Systemsenables consistent and reproducible cfDNA library ...
重测序(re-sequencing):是对有参考基因组物种的不同个体进行的基因组测序,并在此基础上对个体或群体进行差异性分析。主要用于辅助研究者发现单核苷酸多态性位点(SNPs)、拷贝数变异(CNV)、插入/缺失(Indel)等变异类型。 02 如何获得高质量的二代测序数据?
全基因组测序的英文是Whole Genome Sequencing,简称WGS,目前默认指的是人类的全基因组测序。所谓全(Whole),指的就是把物种细胞里面完整的基因组序列从第1个DNA开始一直到最后一个DNA,完完整整地检测出来,并排列好,因此这个技术几乎能够鉴定出基因组上任何类型的突变。对于人类来说,全基因组测序的价值是极大的,它...
[ Ashelford K, Eriksson ME, Allen CM, et al. Full genome re-sequencing reveals a novel circadian clock mutation in Arabidopsis. Genome Biology, 2011, 12(3): 1186-1198 ] 案例2:鸡基因组重测序 背景:鸡是第一个完成基因组序列测定的农业动物(2004年),是研究脊椎动物遗传、进化和发育重要的模式生物...
[ Hunt P, Martinelli A, Modrzynska K, et al. Experimental evolution, genetic analysis and genome re-sequencing reveal the mutation conferring artemisinin resistance in an isogenic lineage of malaria parasites. BMC Genomics, 2010, 11: 499-512 ] ...
Whole genome sequencing (WGS) is becoming the preferred method for molecular genetic diagnosis of rare and unknown diseases and for identification of actionable cancer drivers. Compared to other molecular genetic methods, WGS captures most genomic variat
We performed whole-genome sequencing (WGS) on 40 pairs of primary and recurrent hepatitis B virus (HBV)-related HCC tumors obtained at primary diagnosis and at the time of early recurrence after curative resection. We compared the genetic profiles of the primary and early-recurrent tumors to det...