all different types of use of compounds alkaloids associated with alkylating agents for the diagnosis and treatment of tumors and \\/ or diseases infectedJ. WASSYL NOWICKY
Vesicants are alkylating agents that affect rapidly reproducing and poorly differentiated cells in the body. However, they can also produce cellular oxidative stress, deplete glutathione stores, and promote 5 Types of Disasters 139 intense inflammatory responses. Clinical findings are initially ...
Immunosuppressive therapies, including irradiation, antimetabolites, alkylating agents, cytotoxic drugs, and corticosteroids (used in greater than physiologic doses), may reduce the immune responses to vaccines [see Use In Specific Populations]. Warnings for Gardasil Included as part of the PRECAUTIONS se...
while the legs are much less. With growth, the head decreases in size to adult parameters by adolescence. The larger body surface area-to-mass ratio increases the risk of hypothermia. The decreased ability to shiver is another disadvantage to the pediatric patient as...
A simple, highly efficient, and general strategy for the direct synthesis of amino-(N-alkyl)benzenesulfonamides has been accomplished via direct N-alkylation of aminobenzenesulfonamides bearing both different types of amino groups with alcohols as alkylating agents. Notably, this research exhibited the...
In total 37 drugs were analysed; eight topoisomerase II inhibitors, eight anti-metabolites, eight alkylating agents, eight tubulin-active agents and five compounds with other or unknown mechanisms of action, including one topoisomerase I inhibitor. Correlation analysis of log IC50 values obtained from ...
Antineoplastic Agents, AlkylatingBrain NeoplasmsCarmustineGlioblastomaCombined Modality TherapyDose FractionationMiddle AgedThis study investigated the effects of six attributes, associated with simplicity or attractiveness, on route preference for three pedestrian journey types (everyday, leisure and tourist). ...
GARDASIL, Human Papillomavirus Quadrivalent (Types 6, 11, 16, and 18) Vaccine,Recombinant, is a non-infectious recombinant quadrivalent vaccine prepared from the purified virus-like particles (VLPs) of the major capsid (L1) protein of HPV Types 6, 11, 16, and 18. The L1 proteins are produc...
The present review article gives a description of different classes of inhibitors of 17β-HSD1 (C6-derivatives of E2, C16-derivatives of E2 as alkylating and dual action compounds, E2-adenosine hybrids, E2-simplified adenosine hybrids, and C16-derivatives of E1 or E2) and of inhibitors of 17...
T-cell lymphomas are rare and aggressive malignancies associated with poor outcome, often because of the development of resistance in the lymphoma against