What are the chemical mutagens? Most chemical mutagens are alkylating agents and azides. Physical mutagens include electromagnetic radiation, such as gamma rays, X rays, and UV light, and particle radiation, such as fast and thermal neutrons, beta and alpha particles. What is meant by an allele...
Alkylating agents (cyclophosphamide, ifosfamide, mitomycin C) show modest activity as do the platina compounds. A dose-response relationship has been described with cisplatin. Results with detorubicin and high dose methotrexate need confirmation. Other antifolates are inactive, as are the newer agents...
1) What are the four factors that affect population size over time? 2) What are population cycles? What are some of the factors that drive them? Why is the error rate during DNA replication related to population size? Explain the difference between th...
Question: What are aromatic compounds with reference to structures in organic chemistry? Aromatic compounds: Several general criteria must be met if a molecule is to be aromatic. 1. An aromatic molecule must be cyclic. 2. An aromatic molecule must be planar. ...
As mentioned in the Introduction, there are some advantages demonstrated regarding N-terminal Hb adducts from acrylamide as a measure of internal dose. The N-terminal Hb adducts from acrylamide in humans are stable over the life-time of erythrocytes, according to measurement of decline of adduct ...
With that in mind, here are some considerations that can help you plan ahead when determining when to take off work and how much time away you may need in the course of yourbreast cancer treatment. Average Time Off What’s the Average Time Off for Breast Cancer?
The successful invasions of TEs in genomes, despite their mutational properties, are an apparent paradox. TEs' transposition is usually strongly regulated to low value, but in some cases these elements can also show high transposition rates, which has been associated sometimes to changes in ...
these are some of those mechanisms that might increase tumor aggressiveness without any involvement of HPD. Therefore, one may rightly ask (i) whether these causative factors can be at the basis of both progression of the disease (PD) and HPD and (ii) if and how it is possible to discrimi...
Nitrosamines exert theirtoxic and mutagenic effects by alkylating N-7 of guanine, leading to destabilization and increased breakage of DNA [4–9]. Do cigarettes contain nitrosamines? Tobacco-specific nitrosamines (TSNAs) are thought to be some of the most potent carcinogens in tobacco products. They...
Severe hypertension is seen disproportionately in association with secondary hypertension, and many causes of secondary hypertension are known to result in blood pressure lability, further disposing toward hypertensive crisis. Box 1 lists some of these conditions. ...