antineoplastic,antineoplastic drug,cancer drug- any of several drugs that control or kill neoplastic cells; used in chemotherapy to kill cancer cells; all have unpleasant side effects that may include nausea and vomiting and hair loss and suppression of bone marrow function ...
Financial Encyclopedia Wikipedia </>embed</> Leukeran chlorambucil cancer drug antineoplasti... antineoplastic alkylating... noun Words related to alkylating agent nounan antineoplastic drug used to treat some forms of cancer Related Words antineoplastic ...
Alkylating agents act by cross-linking strands of DNA, particularly at the N-7 position of guanine. They are nonspecific for cell cycle phase and are thus active during most parts of the cell cycle. Alkylating agents in the classic family include nitrogen mustard, cyclophosphamide, chlorambucil...
This paper reviews our current knowledge of the DNA sequence selectivity of alkylating agents such as nitrogen mustards, chloroethylnitrosoureas and other chloroethylating agents, dimethanesulphonates, and ethylating and methylating agents. In general, reaction at the guanine-N7 position for agents ...
30. The method according to claim 1 or 2, wherein said electrophile is selected amongst nitrogen or sulfur mustards, nerve agents, sarin, phosgene, soman, tabun and thionyl chloride, herbicides, pesticides or insecticides, l,2,3,4,10-hexachloro-l,4,4a,5,8,8a-hexahydro-l,4,5,8-dimetha...
Despite the significant amount of research into s-triazine derivatives in recent years, there is a demand for newer agents with unique, but still effective, mechanisms of action to treat microbial diseases. Alkylating agents, in particular nitrogen-based alkylators, are commonly used, and they act...