Powell, Brian D. Green, Jane McEneny, Ann McGinty, The anti-atherogenic effects of eicosapentaenoic and docosahexaenoic acid are dependent on the stage of THP-1 macrophage differentiation, Journal of Functional Foods (2015), doi: 10.1016/j.jff.2014.12.023...
5. F Kianoush, M Nematollahi, J D Waterfield, etc. Regulation of RAW264.7 macrophage polarizat...
NAIP,cIAP1andcIAP2expression during macrophage differentiation and M1/M2 polarization [J]. PloS one...
D3(VD 3)are stimuli commonly used to induce macrophage differentiation in monocytic cell lines but the extent of differentiation in comparison to primary tissue macrophages is unclear.We have compared the phenotype of the promonocytic THP-1cell line after various protocols of differentiation utilising...
Key Words: macrophage atherosclerosis cholesterol triglyceride cyclodextrin F oam cell macrophages are involved in all stages of atherosclerosis. 1 Unregulated uptake of modified LDL, such as acetylated LDL (AcLDL), via the scavenger receptor (ScR), is considered important in the accumulation of unes-...
结论HCMV感染THP-1源性巨噬细胞早期可激活细胞自噬,其激活方式可能并不依赖于HCMV复制,而感染后期细胞自噬受到抑制,这可能与HCMV复制等因素有关,但需进一步实验证实。 关键词: 巨细胞病毒;巨噬细胞;自噬;THP-1源性巨噬细胞 ABSTRACT ObjectiveTo study the autophagy in THP-1 derived macrophage after HCMV inf...
Also, we found that after silencing HHLA2 in AsPC-1 and Capan-2 cells, the expression of M2 macrophage markers were significantly decreased. These results indicated that the M2-type polarization of TAMs can be inhibited after silencing HHLA2. The current study also has limitations. HHLA2 is ...
PMA treatment, which activates protein kinase C (PKC), also induces a greater degree of differentiation in THP-1 cells as reflected by increased adherence and expression of surface markers associated with macrophage differentiation [15]. However, it is unclear how the differentiation state of PMA-...
PMA诱导THP-1步骤：将处于对数生长期的THP-1细胞离心，用RPMI-1640培养基重悬；加入PMA，显微镜下细胞...
THP-1细胞可通过化学物质处理、细胞因子刺激或共培养等方法，诱导其分化为具有巨噬细胞特性的细胞群。机理...