M6A RNA methylation can be involved in the regulation of physiological and pathological processes, including cancer. In this review, we discuss the role of m6A RNA methylation modification plays in tumor metabolism-related molecules and pathways, aiming to show the importance of targeting m6A in ...
The role of m6A RNA methylation in cancer metabolism. Abbreviated Mol Cancer. 2022;21:14. Article CAS Google Scholar Han J, Wang JZ, Yang X, Yu H, Zhou R, Lu HC, Yuan WB, Lu JC, Zhou ZJ, Lu Q, et al. METTL3 promote tumor proliferation of bladder cancer by accelerating pri-...
25,31,32,33,34]. The ability to adapt to changing microenvironments such as that of stress or chemotherapeutic drugs is crucial to ensure survival of tumour cells, indicating that RNA modifications could play important roles in cancer. Historically, cancer has been...
& Ming, L. The role of m6A RNA methylation in cancer. Biomed. Pharmacother. 112, 108613 (2019). Article PubMed CAS Google Scholar Qin, Y. et al. Role of m6A RNA methylation in cardiovascular disease (Review). Int. J. Mol. Med. 46(6), 1958–1972 (2020). Article PubMed PubMed...
Multiple functions of m6A RNA methylation in cancer. J Hematol Oncol. 2018;11:48. Article PubMed PubMed Central Google Scholar Han J, Wang JZ, Yang X, Yu H, Zhou R, Lu HC, Yuan WB, Lu JC, Zhou ZJ, Lu Q, et al. METTL3 promote tumor proliferation of bladder cancer by ...
Recently, immunotherapy represented by immune checkpoint blocking has increasingly become an effective cancer treatment, and increasing shreds of evidence show that m6A RNA methylation affects cancer immunity in various cancers. Until now, there have been few reviews about the role and mechanism of m6A...
N6-methyladenosine (m6A), the most abundant modification in eukaryotic cells, regulates RNA transcription, processing, splicing, degradation, and translation. Circular RNA (circRNA) is a class of covalently closed RNA molecules characterized by universal
Pivotal roles of m6A RNA methylation in cancer Besides the above findings that m6A RNA methylation is critical for normal hematopoietic, central nervous and reproductive systems development, aberrant m6A modification has also been indicated to be associated with various types of human cancers65,158,159...
Biomarker Research (2021) 9:39 https://doi.org/10.1186/s40364-021-00295-8 REVIEW Open Access The emerging role of RNA N6- methyladenosine methylation in breast cancer Fangchao Zheng1†, Feng Du2†, Jiuda Zhao3†, Xue Wang4, Yiran Si1, Peng Jin5, Haili Qian6, Binghe Xu1 and ...
国家卫生健康委员会时间生物学重点实验室(四川大学)屈艺教授和母得志教授团队长期致力于儿科新生儿疾病的研究工作,该团队于去年8月在Biomolecules(影响因子:6.064,JCR Q2区)发表综述文章“Research Progress on the Role of RNA m6A Modification in Glial Cells in the Regulation of Neurological Diseases”。