In response, plant nucleotide-binding leucine-rich repeat proteins recognize specific effectors and mount effector-triggered immunity (ETI). While ETI is pervasive across, with at least 19 families ofeffectors recognized in this model species, the ETI landscapes of crop species have yet to be ...
et al. The transcriptional landscape of Arabidopsis thaliana pattern-triggered immunity. Nat. Plants 7, 579–586 (2021). https://doi.org/10.1038/s41477-021-00874-5 Download citation Received03 December 2020 Accepted08 February 2021 Published15 March 2021 Issue DateMay 2021 DOIhttps://doi.org/...
Puccinia triticinaeffector Pt-1234 modulates wheat immunity by targeting transcription factor TaNAC069 via its C subdomain 小麦叶锈菌效应蛋白Pt-1234靶向结合小麦转录因子TaNAC069亚结构域C调控小麦免疫反应 Huaimin Geng, Yanjun Zhang, Zhen Qin, Shen Wang, Changshan Liu, Zhongchi Cui, Daqun Liu, Haiyan...
An RNA vaccine drives immunity in checkpoint-inhibitor-treated melanoma. Nature 585, 107–112 (2020). CAS PubMed Google Scholar Stevanovic, S. et al. Landscape of immunogenic tumor antigens in successful immunotherapy of virally induced epithelial cancer. Science 356, 200–205 (2017). CAS ...
The Magnaporthe oryzae effector AvrPiz-t targets the RING E3 ubiquitin ligase APIP6 to suppress pathogen-associated molecular pattern-triggered immunity in Rice. Plant Cell. 2012;24(11):4748–62. Article CAS PubMed PubMed Central Google Scholar Ghaffary SMT, Faris JD, Friesen TL, Visser RG,...
Currently, there are limited therapeutic drugs and methods available for treating viral encephalitis, primarily due to the complex pathogenesis in the CNS. In this study, we employed scRNA-seq to generate a comprehensive landscape of cellular composition and immunological phenotype in the brain tissue ...
Tumor-antigen expression reorganizes the immune landscape in KP lung cancer We first profiled immune responses triggered by the LucOS CD8+ T cell antigens 8 weeks after lentiviral infection, a timepoint that represents a transition between a functional and dysfunctional CD8+ T cell response.12,15...
immunotherapies focusing on innate immunity have attracted increasing interest and have shown promising anti-tumor activity by engaging innate cells or innate-like cells, which can be used alone or complement current therapies. In this review, we depict the landscape of BiTE therapy, including clinical...
Plant immune systems have evolved to fend off attack from pathogens via two layers of defense: pathogen-associated molecular patterns (PAMPs)-triggered immunity (PTI) induced by the perception of highly conserved structural motifs in pathogens, and effector-triggered immunity induced by pathogen ...
The same analysis was performed for eight fungal effectors (Fig.6c), including secreted protein 7—RIR_3212100/g18424 (RiSP7), an effector protein involved in biotrophic response to AM colonization77, secreted lysin motif—RIR_1359320 (RiSLM), an effector which reduces chitin-triggered immune re...