Serafini N, Di Santo JP. Effector cells of the mucosal immune system: innate lymphoid cells. In: Mucosal Immunology. Edited by J. Mestecky, W. Strober, M. Russell , H. Cheroutre, B. N. Lambrecht, B. Kelsall, Elsevier 2015Serafini N, Di Santo JP. Effector cells of the mucosal ...
The ‘reinforcement’ of theimmune systemfrom systemic and microenvironmental factors to support the function of effector immune cells: this measures how well the overall microenvironment and other factors could support or suppress the durability of effector cells to kill tumor cells. ...
Cancer Immunotherapy by retargeting of immune effector cells via recombinant bispecific antibody constructs. Antibodies 2012;1:172- 98.Cancer Immunotherapy by retargeting of immune effector cells via recombinant bispecific antibody constructs - Stamova, Koristka, et al....
The mechanisms by which cancer cells evade the immune system should be thoroughly considered, and to include the evaluation of the functional status of the cancer cells, their proliferative and metastatic mechanisms, their metabolic status, the MHC expression which is responsible for displaying the tum...
Injection of such lymphocytes into the foot pads of syngeneic rats leads to enlargement of the regional popliteal lymph nodes and to the development within these nodes of effector lymphocytes which specifically damage syngeneic but not foreign target cells in culture....
Reflecting on the outcome of aspergillosis from the different infection models, we conclude that AM are likely to be important in orchestrating the early immune response to recruit other immune effector cells. However, although able to slow fungal outgrowth, AM are insufficient to clear the infection...
miR-125a stabilizes both the commitment and immunoregulatory capacity of Treg cells. In miR-125a-deficient mice, the balance appears to shift from immune suppression to inflammation, and results in more severe pathogenesis of colitis and experimental autoimmune encephalomyelitis (EAE). The genome-wide...
From tumor immunosuppression to eradication: targeting homing and activity of immune effector cells to tumors.From tumor immunosuppression to eradication: targeting homing and activity of immune effector cells to tumors.doi:10.1155/2011/439053Unraveling the mechanisms used by the immune system to fight ca...
Mast cells (MC) are phylogenetically old cells which are distributed throughout the human organism. MC are found in almost all of the major organs and tissues of the body, particularly in association with connective tissue structures such as blood vessels, lymphatic vessels and nerves, and in pr...
We have used an adoptive transfer system to investigate the point(s) of control within the pathway of EAE effector cell development from MBP-specific naive precursors that prevents clinical disease in T-cell line vaccinated, MBP-CFA challenged Lewis rats. Although EAE effector cells do not...