Serafini N, Di Santo JP. Effector cells of the mucosal immune system: innate lymphoid cells. In: Mucosal Immunology. Edited by J. Mestecky, W. Strober, M. Russell , H. Cheroutre, B. N. Lambrecht, B. Kelsall, Elsevier 2015Serafini N, Di Santo JP. Effector cells of the mucosal ...
B cells have a central role in many autoimmune diseases, including in those with renal involvement, as well as in the immunological response to kidney transplantation. The majority of B cell studies have focused on their pathological role as antibody producers. However, these cells have broad func...
In parallel with a plateau in the frequency of hPBLs, we noted a time-dependent change in the composition of circulating human immune cells (Fig.1B,D). At 2 months post-engraftment, most human immune cells were CD19+B cells (86%). At 4–6 months post-engraftment, the frequency of h...
Tolerance is maintained by multiple mechanisms, including regulatory immune cells, such as regulatory T cells or myeloid-derived suppressor cells (MDSC), immunosuppressive cytokines, and cellular ligand/receptor pairs, named immune checkpoints, which are known to down-modulate immune effector functions. ...
These values are within the confidence interval established for the lifetime of these cells [82]. The rate of effector B-cell elimination (𝜎7=0.028σ7=0.028 day−1) ≈24.75≈24.75 days is consistent with that observed in [83]. In the model of cytokine storm, the rate constant of ...
Human skin has a tough outer layer of cells that producekeratin. This layer of cells, which is constantly renewed from below, serves as a mechanical barrier to infection. In addition, glands in the skin secrete oily substances that includefatty acids, such asoleic acid, that can kill some ...
cells,T regulatory cells(Treg; CD4+,CD25+, Foxp3+) are responsible for limiting the immune response and for immune tolerance to self antigens and therefore they constitute defense against self-directed attack of the immune system[17]. The effector cytokine ofTregcells is anti-inflammatory IL-...
As for the cellular immunity, it was found that the T CD8+lymphocyte subpopulation remained the main potent and long lasting immune active effector regulating tumour growth. 展开 关键词: Modified melanoma cells (B16MOD) Wild-type melanoma cells (B16WT) IGF-1 (insulin-like growth factor-1) ...
Reflecting on the outcome of aspergillosis from the different infection models, we conclude that AM are likely to be important in orchestrating the early immune response to recruit other immune effector cells. However, although able to slow fungal outgrowth, AM are insufficient to clear the infection...
The cells were incubated at room temperature for 25 minutes and then washed in PBS containing saponin. The cells were then resuspended in 1.0% paraformaldehyde for analysis. EBV antibody levels EBV VCA IgG testing was performed using the Merifluor EBV IgG IFA kit (Meridian Bioscience, Inc., ...