XiaoxiaoMa,Timothy A.Chan, inTrends in Cancer, 2022 (i) The capability ofeffector cells, such asT cellsto ‘recognize’ tumor cells: this reflects theimmunogenicityof the tumor, and the pre-existingimmune reactivityagainst the tumor, which is related to the quality and quantity of antigens (...
However, there is considerably disparity with regard to migration of memory/effector cells from mucosal inductive sites to secretory effector sites and ... P Brandtzaeg - 《Vaccine》 被引量: 824发表: 2007年 Humoral immunity to HIV‐1: neutralization and beyond Humoral immunity is considered a ke...
immunity. Cells in the lining of thegastrointestinal tractsecrete mucus that, in addition to aiding the passage of food, can trap potentially harmful particles or prevent them from attaching to cells that make up the lining of the gut. Protective antibodies aresecretedby cells underlying the ...
& Tsai, M. Immunomodulatory mast cells: negative, as well as positive, regulators of immunity. Nat. Rev. Immunol. 8, 478–486 (2008). Article CAS PubMed Google Scholar Moon, T.C. et al. Advances in mast cell biology: new understanding of heterogeneity and function. Mucosal Immunol. 3...
Modified melanoma B16 cells inhibited in their IGF-1 expression (B16MOD), on the contrary to the IGF-1 fully expressed parental wild-type (B16WT) counterpart, were shown to stimulate humoral as well as cellular immune responses. Among humoral components, the neutralizing and complement-fixing ant...
Fc receptors are required in passive and active immunity to melanoma Effective tumor immunity requires recognition of tumor cells coupled with the activation of host effector responses. Fc receptor (FcR) γ−/− Raphael,Clynes,Yoshizumi,... - 《Proceedings of the National Academy of Sciences...
demonstrated a crosstalk between PD-1 and CD134 (OX40) regarding T-helper-cell differentiation and anti-plasmodium humoral immunity in humans [8]. The CD134/OX40L axis is pivotal for the CD4+ differentiation toward effector T-cells. On the other hand, T-cell activation can be dampened by...
Cytotoxic t cells , after sensitization by antigen , are effector cells , especially important in antiviral immunity . 已被抗原致敏的细胞毒性t细胞是效应细胞,在抗病毒免疫中起到特别重要的作用。 What are the effector cells of the humoral immune response ? 体液免疫反应中的免疫体细胞是什麽? How do...
Stoichiometry between antigen and antibody influence immune complex formation and subsequent engagement with Fc domain sensors on host cells and thus effector functions. Antibodies can both provide protection and enhance disease in infections. Emerging tools that systematically probe antibody specificity, affin...
Such interactions might trigger regulatory and cytotoxic responses of γδ T cells, they also induce innate and adaptive immunity, and they can promote tissue repair and wound healing. Although studies in mice have been useful in identifying possible roles for γδ T cells in vivo, several ...