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TGF-beta signaling in cancer--a double-edged sword. Transforming growth factor (TGF) β1 is a potent growth inhibitor, with tumor-suppressing activity. Cancers are often refractile to this growth inhibition ... RJ Akhurst,R Derynck - 《Trends in Cell Biology》 被引量: 1473发表: 2001年 ...
Joan M,et al.(2008) TGF-beta in Cancer. Cell. 134(2): 215–230. Jakowlew SB,et al.(2006) Transforming growth factor-beta in cancer and metastasis. Cancer Metastasis Rev. 25(3):435-57. Derynck R,et al.(2001) TGF-beta signaling in tumor suppression and cancer progression. Nat Gen...
TGF-beta: an important medi- ator of allergic disease and a molecule with dual activity in cancer development. J Immunol Res. 2014;2014:318481.TGF- β : An Important Mediator of Allergic Disease and a Molecule with Dual Activity in Cancer Development[J] . Belen Tirado-Rodriguez,Enrique ...
231 breast cancer cells and HONE-1 nasopharyngeal carcinoma cells without TGF-beta 1 treatment, while GSN expression was increased with TGF-beta 1 ... 陳智源,Chen, ZhiYuan - 《中興大學生命科學系所學位論文》 被引量: 0发表: 2013年 TGFβ signalling: a complex web in cancer progression and tu...
TGF-β regulates both the tumor-forming and migratory abilities of various types of cancer cells. However, it is unclear how the loss of TGF-β signaling components affects these abilities in clear-cell renal cell carcinoma (ccRCC). In this study, we inv
TGF-beta has mostly been researched in cancer cells. Its impact on cancer in humans is unknown. Remember that many substances and their related pathways have anti-cancer effects in cells. This doesn’t mean that they have any medical value. On the contrary, most pathways that are researched ...
TGF-beta 1 belongs to a family of pluripotent growth factors (TGF beta s) and has been implicated in the development and progression of human breast cancer. There are conflicting data though, suggesting that TGF-beta has the pontency both to promote and inhibit the progression of mammary neopl...